ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025
Alzheimer's disease and dementia in Japan: Epidemiological trends, regional disparities, and future projections.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Autism: epidemiology, genetics, molecular mechanisms, clinical features, diagnosis, and management.Molecular biomedicine · 2026Review
- The growing burden of dementia in Asia: Comparative insights from Japan, China, and India.The journal of prevention of Alzheimer's disease · 2026Article
- Epidemiological and clinical evidence on blood pressure management for the prevention of dementia: striving for a healthy 100-year life.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Forecast of dementia prevalence in Germany and subnational regions until 2060 using microsimulation.European journal of epidemiology · 2026Article
- Identifying priority diseases and injuries to promote equality as measured by health-adjusted life expectancy: a population-based study.BMJ global health · 2026Article
- The potential for dementia prevention in Japan: a population attributable fraction calculation for 14 modifiable risk factors and estimates of the impact of risk factor reductions.The Lancet regional health. Western Pacific · 2026Article
- The divergent effects of population aging: comparative analysis of the burden of Alzheimer's disease and other dementias in China and G20 countries, 1990-2050.American journal of translational research · 2026Article
- Alzheimer's disease and dementia in Japan: Epidemiological trends, regional disparities, and future projections.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Global burden and trends of occupational noise-induced hearing loss (1990-2021) and projection to 2040.Frontiers in public health · 2025Article
- National trends in cerebrospinal fluid biomarker testing for Alzheimer's disease in Japan.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlzheimer's disease and other dementias (ADOD) are a growing public health concern in Japan. This study examines historical ADOD burden trends, identifies contributing risk factors, and forecasts future projections using time-series modeling.
methodsThis study uses the Global Burden of Disease (GBD) study 2021 data to analyze ADOD trends in Japan, and assess incidence, mortality, and Disability-adjusted life years (DALYs). Regression analysis identifies risk factors, and an Autoregressive Integrated Moving Average (ARIMA) model is employed to forecasts the burden from 2021 to 2030.
resultsADOD cases have steadily increased, with projections indicating continued growth by 2030. Aging and life expectancy are major contributors, with urban areas like Kantō and Kansai region experiencing higher prevalence than Tōhoku and Kyūshū. High fasting plasma glucose, obesity, and smoking are significant modifiable risk factors. The ARIMA model forecasts an ongoing upward trend, highlighting a rising public health challenge. DISCUSSION: Targeted policies, early interventions, and equitable health care access are vital to mitigating Japan's growing ADOD burden. HIGHLIGHTS: Alzheimer's disease and other dementias (ADOD) are rising in Japan due to an aging population. Key risk factors include high fasting plasma glucose, obesity, and smoking. Kantō and Kansai region have higher ADOD prevalence than other region ARIMA modeling predicts a continuous increase in ADOD cases through 2030. Targeted health care policies and preventive measures are crucial to mitigate the burden.
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