Evidence map›Paper›PMID 40631405›Full record

Trial reportJournal of the International Society of Sports Nutrition2025

Caffeinated chewing gum produces comparable strength and power gains to capsules with fewer side effects in resistance-trained men.

Li Ding, Jue Liu, Yixuan Ma, Litian Bai, Li Guo, Bin Chen, Yinhang Cao, Olivier Girard

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li DingShanghai University of Sport, Key Laboratory of Exercise and Health Sciences (Ministry of Education)School of Athletic Performance, Shanghai, China.
Jue LiuFudan University, Department of Rehabilitation Medicine, Huashan Hospital, Shanghai, China.ORCID 0000-0003-1634-9904
Yixuan MaShanghai University of Sport, Key Laboratory of Exercise and Health Sciences (Ministry of Education)School of Athletic Performance, Shanghai, China.
Litian BaiShanghai University of Sport, School of Athletic Performance, Shanghai, China.
Li GuoShanghai University of Sport, School of Exercise and Health, Shanghai, China.
Bin ChenFujian Agriculture and Forestry University, Department of Public Physical Education, Fuzhou, China.
Yinhang CaoShanghai University of Sport, Key Laboratory of Exercise and Health Sciences (Ministry of Education)School of Athletic Performance, Shanghai, China.ORCID 0000-0003-2323-3707
Olivier GirardThe University of Western Australia, School of Human Sciences (Exercise and Sport Science), Perth, Australia.ORCID 0000-0002-4797-182X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCaffeine, widely used as an ergogenic aid, has been extensively studied regarding its dosage and timing of ingestion. However, the impact of different administration methods on caffeine's performance-enhancing effects remains relatively underexplored. This study compared the effects of caffeine administered via chewing gum versus capsules on maximal strength, muscular power, and side effects during bench press and back squat exercises.

methodsSixteen resistance-trained males participated in a double-blind, randomized trial, ingesting either a 4 mg/kg caffeine capsule (CC) or placebo capsule (PC) one hour before testing, or a 4 mg/kg caffeinated gum (CG) (4 mg/kg) or placebo gum (PG) five minutes prior. Assessments including one-repetition maximum (1RM) and muscular power at 25%, 50%, 75%, and 90%1RM for bench press and back squat.

resultsCaffeine increased 1RM (+2.1-5.0%) and muscular power (+6.1-20.0%) in both the bench press and back squat compared to placebo (all

conclusionCaffeinated gum (4 mg/kg) produced ergogenic effects comparable to capsules in enhancing maximal strength and muscular power during bench press and back squat exercises, with fewer side effects in resistance-trained men.

Indexed as

CaffeineChewing GumMuscle StrengthPerformance-Enhancing SubstancesResistance TrainingAdultCapsulesDouble-Blind MethodHumansMaleWeight LiftingYoung AdultCaffeineCapsulesChewing GumPerformance-Enhancing Substancescaffeine administrationErgogenic aidload-power relationshipone-maximum repetitionresistance exercise

Identifiers

PMID40631405
PMCPMC12243013

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.