Evidence map›Paper›PMID 40631350›Full record

ArticleEpigenetics reports2025

Maternal Diet Quality in Pregnancy and Human Milk Extracellular Vesicle and Particle microRNA.

Meghan E Muse, Yuting Wang, Diane Gilbert-Diamond, David A Armstrong, Anne G Hoen, Megan E Romano, Jiang Gui, Thomas J Palys, Frederick W Kolling, Brock C Christensen and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epigenetics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Meghan E MuseDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH, USA.
Yuting WangDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH, USA.
Diane Gilbert-DiamondDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH, USA.
David A ArmstrongResearch Service, V.A. Medical Center, White River Junction, VT, USA.
Anne G HoenDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH, USA.
Megan E RomanoDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH, USA.
Jiang GuiDepartment of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Thomas J PalysDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH, USA.
Frederick W KollingDartmouth Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Brock C ChristensenDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH, USA.
Margaret R KaragasDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH, USA.
Caitlin G HoweDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, 1 Medical Center Dr, Lebanon, NH, USA.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3M
Relation Between In-utero Vitamin D and Immune Function in Early Childhood P20GM104416 · NIGMS · DARTMOUTH COLLEGE · PI SALAS DIAZ, LUCAS A · 2013 to 2022
$23.7M
Training Program for Quantitative Population Sciences in CancerT32CA134286 · NCI · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA, TOSTESON, TOR D · 2020 to 2024
$1.5M
Prenatal Metal Mixtures, Fetal Growth, and the Role of MicroRNAsR00ES030400 · NIEHS · DARTMOUTH COLLEGE · PI HOWE, CAITLIN GRACE · 2020 to 2022
$726k
Acquisition of the NextSeq2000 Sequencing platform to Increase Next Generation Sequencing Throughput While Reducing Costs at DartmouthS10OD030242 · OD · DARTMOUTH COLLEGE · PI KOLLING IV, FRED W · 2021 to 2021
$321k
NCI NIH HHS P30 CA023108NCI NIH HHS T32 CA134286NIEHS NIH HHS R00 ES030400NIGMS NIH HHS P20 GM104416NIH HHS S10 OD030242NIH HHS UH3 OD023275
6 · The paper itself

Abstract

Extracellular vesicle and particle microRNAs (EVP miRNA) in milk have the capacity to facilitate maternal-infant communication in the postpartum period and are hypothesized to play important roles in child development. Maternal diet quality has been linked to milk macronutrient composition, microbiota profiles, as well as various child health outcomes. The aim of this study was to assess the association between maternal diet quality and milk EVP miRNA. In a pilot study of 54 participants from a larger birth cohort study, diet quality was measure by the Alternative Healthy Eating Index 2010 (AHEI-2010) during the second trimester of pregnancy and 798 EVP miRNA were profiled in mature milk samples (collected approximately six weeks postpartum) using the NanoString nCounter platform. In covariate-adjusted models, AHEI-2010 was positively associated (

Indexed as

Alternative Healthy Eating Index 2010Diet QualityExtracellular VesicleHuman MilkmiRNAPregnancy

Identifiers

PMID40631350
PMCPMC12234000

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.