Evidence map›Paper›PMID 40631314›Full record

ArticlebioRxiv : the preprint server for biology2025

Genome-wide analysis reveals pathways important for the development and maturation of excitatory synaptic connections to GABAergic neurons.

Devyn B Oliver, Shankar Ramachandran, Kasturi Biswas, Claire Y Bénard, Maria Doitsidou, Hailey McKillop, Noelia Genao, Michele L Lemons, Michael M Francis

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Molecular Physiology of the Neuronal Synapse.Current issues in molecular biology · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Shankar RamachandranORCID 0000-0002-1299-4482
Hailey McKillop
Noelia Genao
Michele L Lemons
Michael M FrancisORCID 0000-0002-8076-6668

Funding

Molecular Analysis of Neural Circuit Excitation and InhibitionR01NS064263 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FRANCIS, MICHAEL M · 2009 to 2025
$5.5M
In vivo genetic analysis of dendritic spine development and maintenanceF31NS103365 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI OLIVER, DEVYN BLAIR · 2018 to 2020
$89k
NINDS NIH HHS F31 NS103365NINDS NIH HHS R01 NS064263
6 · The paper itself

Abstract

A high degree of cell and circuit-specific regulation has presented challenges for efforts to precisely define molecular mechanisms controlling synapse formation and maturation. Here, we pursue an unbiased forward genetic approach to identify

Identifiers

PMID40631314
PMCPMC12236491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.