Evidence map›Paper›PMID 40631302›Full record

ArticlebioRxiv : the preprint server for biology2025

AMPK alters proteasome phosphorylation status and prevents persistent proteasome condensates.

Jianhui Li, Conner Butcher, Kyle VanderVen, Mark Hochstrasser

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jianhui LiDepartment of Biomedical Engineering and Science, Florida Institute of Technology, Melbourne, FL 32901.ORCID 0000-0001-8809-845X
Conner ButcherDepartment of Biomedical Engineering and Science, Florida Institute of Technology, Melbourne, FL 32901.
Kyle VanderVenDepartment of Biomedical Engineering and Science, Florida Institute of Technology, Melbourne, FL 32901.
Mark HochstrasserDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.

Funding

Mechanisms of Cell Regulation and Manipulation by the Ubiquitin SystemR35GM136325 · NIGMS · YALE UNIVERSITY · PI Mark W Hochstrasser · 2020 to 2026
$6.5M
6500 QTrap Mass Spectrometer for Yale UniversityS10OD018034 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2014 to 2014
$514k
An Ultra-Performance Liquid Chromatography System to Support Metabolomics at Yale UniversityS10OD019967 · OD · YALE UNIVERSITY · PI LAM, TUKIET T · 2015 to 2015
$135k
NIGMS NIH HHS R35 GM136325NIH HHS S10 OD018034NIH HHS S10 OD019967
6 · The paper itself

Abstract

Proteasomes are large multiprotein complexes required for selective intracellular protein degradation, regulating numerous cellular processes and maintaining protein homeostasis and organismal health. In the budding yeast

Indexed as

AMPKBudding yeastGlucose starvationNucleocytoplasmic translocationPhosphorylationProteasome condensate

Identifiers

PMID40631302
PMCPMC12236653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.