ArticleJTCVS open2025
Acute kidney injury after heart valve surgery: Incidence and impact on mortality based on serum creatinine and urine output criteria.
Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and risk factors of acute kidney injury following Stanford type A aortic dissection surgery: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Pooled it
- The Price of Redo Mitral Valve Replacement: Determinants of Major Adverse Postoperative Events.Journal of cardiovascular development and disease · 2026Article
- Association between Creatinine Trajectories and All-Cause Mortality in Elderly Patients after Cardiac Surgery: A Retrospective Cohort Study Based on MIMIC-IV.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026Article
- New Insights in Assessing AKI 3 Risk Factors and Predictors Associated with On-Pump Surgical Aortic Valve Replacement.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The reported incidence of postoperative acute kidney injury (AKI) after cardiac surgery varies depending on the definition used. This study assessed the incidence and predictors of AKI and examined its association with clinical outcomes in patients undergoing heart valve surgery with the use of cardiopulmonary bypass (CPB). Methods: We analyzed 4044 consecutive patients (mean age 60.1 ± 13.3 years; 1862 females) who underwent heart valve surgery between 2013 and 2021. Patients on hemodialysis or mechanical circulatory support and patients undergoing circulatory arrest were excluded. AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Logistic regression analysis was performed to identify predictors of AKI and estimate its probability. Results: AKI occurred in 1261 patients (31.2%), with KDIGO stage 1 the most prevalent (n = 791; 19.6%). Operative mortality was proportionately higher in patients with more severe stages of AKI (2.6% in stage 2% and 17.7% in stage 3). A total of 502 patients died during a median follow-up of 5.7 years. AKI stage 2 (hazard ratio, 2.01; Conclusions: AKI occurs in 31.2% of patients after heart valve surgery, as defined by the KDIGO criteria. Severe AKI is associated with increased overall mortality. Prolonged CPB time is related to severe AKI, particularly in patients with preoperative renal dysfunction.
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