Evidence map›Paper›PMID 40630918›Full record

ArticlePNAS nexus2025

Rapid adaptation to a globally introduced virulent pathogen in a keystone species.

Loren Cassin-Sackett, Mirian T N Tsuchiya, Rebecca B Dikow

Abstract read
In one paragraph

Article in PNAS nexus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Loren Cassin-SackettDepartment of Integrative Biology, University of South Florida, Tampa, FL 33620, USA.ORCID https://orcid.org/0000-0002-6000-4789
Mirian T N TsuchiyaData Science Lab, Office of the Chief Information Officer, Smithsonian Institution, Washington, DC 20024, USA.
Rebecca B DikowData Science Lab, Office of the Chief Information Officer, Smithsonian Institution, Washington, DC 20024, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging infectious diseases are one of the foremost contemporary threats to biodiversity conservation. Outbreaks of novel pathogens can lead to the extinction of host populations, loss of gene flow due to extirpation, and bottlenecks in host populations with surviving individuals. In outbreaks with survivors, pathogens can exert strong selection on hosts, in some cases leading to the evolution of resistance or tolerance in the host population. The pathogen causing sylvatic plague,

Indexed as

evolution of resistanceimmunityparallel evolutionrapid adaptationtemporally fluctuating selection

Identifiers

PMID40630918
PMCPMC12235602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.