Evidence map›Paper›PMID 40630898›Full record

ReviewFrontiers in cardiovascular medicine2025

Artificial intelligence in atrial fibrillation: emerging applications, research directions and ethical considerations.

Ibrahim Antoun, Ahmed Abdelrazik, Mahmoud Eldesouky, Xin Li, Georgia R Layton, Mustafa Zakkar, Riyaz Somani, G André Ng

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Beyond the Biopsy: Imaging Frontiers in Cardiac Sarcoidosis.Cardiology research and practice · 2026
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ibrahim AntounDepartment of Cardiology, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
Ahmed AbdelrazikDepartment of Cardiology, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
Mahmoud EldesoukyDepartment of Cardiology, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
Xin LiDepartment of Cardiovascular Sciences, Clinical Science Wing, Glenfield Hospital, University of Leicester, Leicester, United Kingdom.
Georgia R LaytonDepartment of Cardiovascular Sciences, Clinical Science Wing, Glenfield Hospital, University of Leicester, Leicester, United Kingdom.
Mustafa ZakkarDepartment of Cardiovascular Sciences, Clinical Science Wing, Glenfield Hospital, University of Leicester, Leicester, United Kingdom.
Riyaz SomaniDepartment of Cardiology, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
G André NgDepartment of Cardiology, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most prevalent sustained arrhythmia and a major contributor to stroke and heart failure. Despite progress in management, challenges persist in early detection, risk stratification, and personalised treatment. Artificial intelligence (AI), especially machine learning (ML) and deep learning (DL), has emerged as a transformative tool in AF care. This scoping review examines the applications of AI across key domains: detection, risk prediction, treatment optimisation, and remote monitoring. AI-driven models enhance AF detection by analysing ECGs and wearable device data with high accuracy, enabling early identification of asymptomatic cases. By incorporating diverse clinical, imaging, and genomic data, predictive models outperform conventional risk scores in estimating stroke risk and disease progression. In treatment, AI assists in personalised anticoagulation decisions, catheter ablation planning, and optimising antiarrhythmic drug selection. Furthermore, AI-powered remote monitoring integrates wearable-derived insights with real-time decision support, improving patient engagement and adherence. Despite these advances, significant challenges persist, including algorithm transparency, bias, data integration, and regulatory hurdles. Explainable AI (XAI) is crucial to ensure clinician trust and facilitate implementation into clinical workflows. Future research should focus on large-scale validation, multi-modal data integration, and real-world AI deployment in AF management. AI has the potential to revolutionise AF care, shifting from reactive treatment to proactive, personalised management. Addressing current limitations through interdisciplinary collaboration will be key to realising AI's full potential in clinical practice and improving patient outcomes.

Indexed as

artificial intelligenceatrial fibrillationECGmachine learningpersonalised medicineremote monitoringrisk stratification

Identifiers

PMID40630898
PMCPMC12234536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.