Evidence map›Paper›PMID 40630858›Full record

ArticleFrontiers in neuroscience2025

Delta-fast ripple coupling suppression: designing a brain-mimetic stimulation paradigm for seizure abolishment.

Uilki Tufa, Joshua A Dian, Anya Zahra, Chiping Wu, Liang Zhang, Peter L Carlen, Berj L Bardakjian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Uilki Tufa *Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Joshua A Dian *Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Anya ZahraKrembil Research Institute, University Health Network, Toronto, ON, Canada.
Chiping WuKrembil Research Institute, University Health Network, Toronto, ON, Canada.
Liang ZhangKrembil Research Institute, University Health Network, Toronto, ON, Canada.
Peter L CarlenInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Berj L BardakjianInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep brain stimulation can be an effective alternative treatment for patients that are intractable to antiseizure medication and do not meet surgical inclusion criteria. Clinical trials have demonstrated the safety of thalamic stimulation using a high frequency stimulus but with limited efficacy. Our group has previously shown,

Indexed as

brain-mimeticdeep brain stimulation (DBS)epilepsyphase-amplitude couplingthalamic stimulation

Identifiers

PMID40630858
PMCPMC12236182

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.