Evidence map›Paper›PMID 40630851›Full record

ArticleBeyoglu eye journal2025

8-to-10-Year Follow-Up Results of Photorefractive Keratectomy and Risk Factors for Myopia Regression (Including Near Work Activity) in Southeast Iran.

Sahar Mohaghegh, Haleh Kangari, Shahram Bamdad, Saeed Rahmani

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Article in Beyoglu eye journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Sahar MohagheghDepartment of Optometry, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Haleh KangariDepartment of Optometry, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahram BamdadDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Saeed RahmaniDepartment of Optometry, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the 8-to-10-year safety, efficacy, and predictability of photorefractive keratectomy (PRK) and to assess the risk factors for myopic regression and the role of near-work activity in myopia progression. Methods: This retrospective study included patients who underwent mechanical PRK and were followed up for 8-10 years. Pre-operative clinical data, including visual acuity, refraction, tomography, optical zone, and ablation depth, were analyzed. Safety, efficacy, and predictability indices were evaluated, and astigmatism correction was assessed using Alpins' vector analysis. Myopic regression was defined as a spherical equivalent <-0.25 D. Risk factors for myopic regression were evaluated using regression analysis, and near-work activity was investigated as a potential factor for myopia progression. Results: Eighty-two patients (mean age 30±5.8 years) completed the follow-up. Pre-operative and post-operative refractive errors were -3.61±1.80 D and -0.12±0.25 D, respectively (p<0.001). Seventy-four percent of patients had post-operative refractive errors within ±0.25 D. The safety, efficacy, and predictability indices were 1, 0.95, and 0.97, respectively. The astigmatism correction index was 1.02±0.78. Myopic regression occurred in 22% of patients. Regression analysis showed that the odds of myopic regression increased by 1.4 times (p=0.04) for each 1 D increase in myopia and by 1.05 times (p=0.04) for each micrometer increase in ablation depth. Conversely, the odds decreased by 0.14 times (p=0.03) with each millimeter increase in corneal diameter. The odds ratio for the time spent on near-work activity was insignificant. Conclusion: PRK proved to be a safe, effective, and predictable procedure in the long term. Myopia and ablation depth were significant risk factors for myopic regression, while corneal diameter was protective. Near-work activity did not affect myopia progression. Under-corrected eyes for astigmatism exhibited a higher magnitude of pre-operative astigmatism compared to over-corrected eyes.

Indexed as

Astigmatismmyopiaphotorefractive keratectomyrefractive error

Identifiers

PMID40630851
PMCPMC12231249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.