Evidence map›Paper›PMID 40630817›Full record

ArticleThe archives of bone and joint surgery2025

Lumbosacral Vertebral Angles can Predict Lumbosacral Transitional Vertebrae on Routine Sagittal MRI.

Farrokh Seilanian Toosi, Bahare Mahdianfar, Ahmadreza Zarifian, Ehsan Keykhosravi, Amir Mahmoud Ahmadzadeh, Maryam Ghandhari, Farzaneh Khoroushi, Maryam Emadzadeh, Hormoz Abedi, Behzad Aminzadeh

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Article in The archives of bone and joint surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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10 authors.

Farrokh Seilanian ToosiDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Bahare MahdianfarDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ahmadreza ZarifianDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ehsan KeykhosraviDepartment of Neurosurgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Amir Mahmoud AhmadzadehDepartment of Radiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Maryam GhandhariDepartment of Radiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Farzaneh KhoroushiDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Maryam EmadzadehClinical Research Development Unit, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Hormoz AbediMedical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Behzad AminzadehDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We aimed to measure lumbosacral vertebral angles in routine lumbar sagittal MRIs and assess their association with lumbosacral transitional vertebrae (LSTV). Methods: We recruited 220 patients referring to our hospital for routine lumbar MRI during 2020-2021. All the participants were subject to routine sagittal lumbar MRI, whole spine localizer scan, and coronal MRI to numerate lumbar vertebrae. Five vertebral angles (A, B, C, D, and delta) and dehydration in L4-L5 and L5-S1 discs were assessed in sagittal MRI scans. Data were analyzed using SPSS 26. Results: Out of 220 participants (mean age: 44.29 ± 14.14 years), 36 (16.36%) were diagnosed with LSTV. Among those diagnosed with LSTV, L5-S1 dehydration was less frequently observed compared to other participants (P < 0.001). Multivariate regression showed that dehydrated L4-L5 disc, non-dehydrated L5-S1 disc, increased A-angle, and decreased D-angle can independently predict LSTV. The median A-angle was significantly larger in LSTV patients than in non-LSTV participants (P = 0.038), while the medians of C-angle, D-angle, and delta-angle were significantly smaller in the LSTV group (P < 0.05). A C-angle ≤ 35.5˚ could diagnose LSTV with sensitivity and specificity of 72.2% and 57.6%, respectively. A delta angle ≤ 8.5˚ could diagnose type 2 LSTV with 92.3% sensitivity and 87.9% specificity. Conclusion: Measuring lumbosacral vertebral angles, especially delta-angle, in routine sagittal MRI can potentially alert physicians of a likely LSTV diagnosis.

Indexed as

AngleDiagnosisLumbosacral transitional vertebraeMagnetic resonance imaging

Identifiers

PMID40630817
PMCPMC12232574

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