ArticleFrontiers in plant science2025
Multiomic analysis of the synthetic pathways of secondary metabolites in tobacco leaves at different developmental stages.
Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Comparative RNA-Seq and Phytochemical Profiling Reveal Year-Dependent Bioactive Variations and Delineate Key Metabolic Pathways inInternational journal of molecular sciences · 2026Article
- Metabolic engineering for tobacco quality improvement: Advances and perspectives.Metabolic engineering communications · 2026Review
- Genome-wide identification and functional characterization ofFrontiers in plant science · 2026Article
- Fertilizer placement modulates the effects of soil metabolite formulations on nutrient status, phenylpropanoid-flavonoid metabolism, and sensory quality in flue-cured tobacco.Frontiers in plant science · 2026Article
- Integrative metabolomic and transcriptomic analyses reveal key mechanisms of lignan biosynthesis during sesame (Sesamum indicum L.) seed development.BMC plant biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Methods: To better understand the molecular regulatory mechanisms underlying the biosynthesis of secondary metabolites, particularly flavonoids, during Results: Based on our transcriptomic and metabolomic data, 25 unigenes exhibiting stage-specific expression patterns that were strongly associated with flavonoid accumulation were identified. We found that during early developmental stages (T1-T2), upregulated expression of chalcone synthase (CHS) and chalcone isomerase (CHI) correlated with enhanced flavonoid backbone biosynthesis. In contrast, during the later stage (T3), increased expression of dihydroflavonol 4-reductase (DFR) and anthocyanidin synthase (ANS) was consistent with elevated anthocyanin accumulation. Conclusion: This study systematically analyzed the coordinated regulatory network of flavonoid biosynthesis during leaf development in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.