Evidence map›Paper›PMID 40630718›Full record

ArticleFrontiers in pediatrics2025

Risk factors for early wheezing in preterm infants: a retrospective cohort study.

Xun Chen, Minjing Yang, Jun Xie, Shengzhu Huang, Xiaolian Qin, Zhijian Pan, Maoling Zhu, Dingyuan Zeng, Yifeng Huang, Tao Liang and 2 more

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Understanding recurrent wheezing: A parent's guide.World journal of clinical pediatrics · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xun Chen *Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Minjing Yang *Department of Student Affairs, Yulin Campus of Guangxi Medical University Yulin, Guangxi, China.
Jun XieDepartment of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Shengzhu HuangCenter for Genomic and Personalized Medicine, Guangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Collaborative Innovation Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Xiaolian QinDepartment of Medical Services Section, Maternal & Child Health Hospital of Yulin, Yulin, Guangxi, China.
Zhijian PanDepartment of Gynecology and Obstetrics, Maternal & Child Health Hospital of Qinzhou, Qinzhou, Guangxi, China.
Maoling ZhuDepartment of Obstetrics, Maternal & Child Health Hospital of Nanning, Nanning, Guangxi, China.
Dingyuan ZengDepartment of Gynecology and Obstetrics, Maternal & Child Health Hospital of Liuzhou, Liuzhou, Guangxi, China.
Yifeng HuangDepartment of Gynecology and Obstetrics, Maternal & Child Health Hospital of Guigang, Guigang, Guangxi, China.
Tao LiangDepartment of Pediatrics, Maternal & Child Health Hospital of Wuzhou, Wuzhou, Guangxi, China.
Chunmei LiangDepartment of Gynecology and Obstetrics, Maternal & Child Health Hospital of Yuzhou, Yulin, Guangxi, China.
Guangmin NongDepartment of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The related factors that cause recurrent wheezing in children are complex, and premature delivery may be one of the reasons. Little is known about early wheezing in preterm infants. Methods: Data sourced from 1,616 children born between 2007 and 2013 from 8 hospitals of Guangxi in China. All children were followed by telephone or questionnaire through the sixth year of life. Children were grouped by characters of age: Group A: gestational age (GA ≤ 32 weeks, Group B: 32 weeks < GA < 37 weeks, Group C: 37 weeks ≤ GA < 42 weeks. Results: The incidence and the risk factors of early wheezing in preterm infants were analyzed. The incidence of early wheezing: Group A > Group B > Group C. In Group A, the proportion of small-for-gestational-age (SGA) infant was higher in early wheezing group than in normal group ( Conclusions: Lower gestational age is associated with higher wheezing risk. Preterm infants have higher persistent wheezing incidence than full-term infants. Preterm infants with gestational age <32 weeks have higher transient wheezing incidence than those with gestational age 32-37 weeks or full-term infants. In preterm infants <32 weeks, small for gestational age (SGA) is a potential factor for wheezing. In preterm infants aged 32-37 weeks, male sex, personal allergy history, and family allergy history are potential factors for wheezing, with male sex and family allergy history being significant risk factors.

Indexed as

allergygestational agepreterm infantsrisk factorswheezing

Identifiers

PMID40630718
PMCPMC12234546

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.