ArticleOncology letters2025
Prognostic predictive value of the preoperative systemic immunoinflammatory index combined with the neutrophil-to-lymphocyte ratio in patients with primary liver cancer undergoing transarterial chemoembolization.
Article in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Analysis of the efficacy of camrelizumab/cetuximab neoadjuvant therapy in patients with loco-regionally advanced laryngeal and hypopharyngeal cancer and the prognostic value of NLR/SII.World journal of surgical oncology · 2026Article
- NLR-PALBI Score and Its Grading: Predicting Overall Survival of Patients with Primary Liver Cancer Undergoing Transcatheter Arterial Chemoembolisation.Journal of hepatocellular carcinoma · 2026Article
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12 authors.
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Abstract
Primary liver cancer (PLC) is a common type of malignant tumor, characterized by high morbidity and mortality worldwide, a poor prognosis, and a lack of reliable and effective prognostic predictors. The systemic immunoinflammatory index (SII) and the neutrophil-to-lymphocyte ratio (NLR) are key indicators of immunoinflammation in the body, and their combined clinical utility has not been fully explored in patients with PLC undergoing transarterial chemoembolization. In the present study, the association between the preoperative SII combined with the NLR and the prognosis of patients with PLC undergoing percutaneous hepatic artery chemoembolization was investigated. Of the 311 patients diagnosed with PLC in Liuzhou Hospital of Traditional Chinese Medicine (Liuzhou, China) between March 2017 and October 2019, 122 were included in the study. The clinical data were collected, and the patients were categorized into a low SII group (SII <381.79; 45 patients) and a high SII group (SII ≥381.79; 77 patients), and a low NLR group (NLR <2.83; 55 patients) and a high NLR group (NLR ≥2.83; 67 patients) based on the optimal preoperative SII and NLR cutoff values. The predictive efficacy of SII and NLR on the prognosis of patients with PLC was analyzed using the area under the curve (AUC) of the receiver operating characteristic (ROC) curve. The association between SII, NLR and clinicopathological parameters was analyzed using a χ
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