Evidence map›Paper›PMID 40630629›Full record

ArticleChemical science2025

Insights from designing an artificial cascade catalysis system using principles from substrate channeling in enzymes.

Frances A Houle, Peter Agbo, Junko Yano

Abstract read
In one paragraph

Article in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Frances A HouleChemical Sciences Division, Lawrence Berkeley National Laboratory Berkeley CA 94720 USA fahoule@lbl.gov.ORCID https://orcid.org/0000-0001-5571-2548
Peter AgboChemical Sciences Division, Lawrence Berkeley National Laboratory Berkeley CA 94720 USA fahoule@lbl.gov.ORCID https://orcid.org/0000-0003-3066-4791
Junko YanoMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory Berkeley CA 94720 USA.ORCID https://orcid.org/0000-0001-6308-9071

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Generalizing the key requirements of highly-selective, multi-step chemical conversions involving spatially separated reaction centers remains one of the grand challenges of chemistry. Much work towards this effort has focused on decomposing multi-step conversions into their constituent reactions, whose intermediates are successively upgraded in a chemical cascade

Identifiers

PMID40630629
PMCPMC12231582

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.