Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04338360 (Expanded Access to Convalescent Plasma for the Treatment of Patients With COVID-19), which is not on this map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Katelyn A BrunoDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida.
R Scott WrightDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-0625-0444
Joshua CulbersonDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida.
Mikolaj A WieczorekDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida.
David O HodgeDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida.ORCID 0000-0001-5148-9174
Patrick W JohnsonDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida.ORCID 0000-0001-8365-1375
Yomary A JimenezDivision of Cardiovascular Medicine, University of Florida, Gainesville, Florida.
Emily R WhelanDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida.
Jose M MalavetDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida.
Kathryn F LarsonDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-2565-3318
Jonathon W SenefeldDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-8116-3538
Chad C WigginsDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Stephen A KlassenDepartment of Kinesiology, Brock University, St. Catharines, Ontario, Canada.ORCID 0000-0002-4560-8728
Jacob RicciDivision of Cardiovascular Medicine, University of Florida, Gainesville, Florida.ORCID 0000-0001-6752-1423
Taimur SherDepartment of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, Florida.
Rickey E CarterDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida.ORCID 0000-0002-0818-273X
Michael J JoynerDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-7135-7643
DeLisa FairweatherDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida.ORCID 0000-0003-3093-1810
Allan S JaffeDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-1183-3959
Funding
Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
DIABETES AND METABOLISMT32DK007352 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1986 to 2026
$9.4M
Variant Hemoglobin and Cardiorespiratory Regulation in HumansR35HL139854 · NHLBI · MAYO CLINIC ROCHESTER · PI JOYNER, MICHAEL J · 2018 to 2024
$5.8M
Role of mitochondrial extracellular vesicles in CVB3 myocarditis by sexR01HL164520 · NHLBI · MAYO CLINIC JACKSONVILLE · PI FAIRWEATHER, DELISA · 2022 to 2025
$3.0M
Role of viral mitophagosomes in driving sex differences in myocarditisR21AI145356 · NIAID · MAYO CLINIC JACKSONVILLE · PI FAIRWEATHER, DELISA, SIN, JON · 2019 to 2020
$463k
Vitamin D Binding Protein (DBP) in Innate Immune Cell Response in Viral MyocarditisR21AI163302 · NIAID · UNIVERSITY OF FLORIDA · PI BRUNO, KATELYN ANN · 2021 to 2022
$430k
Adipose-derived biogenic nanoparticles for treatment of myocarditis/DCM(MPDPI)R21AI152318 · NIAID · MAYO CLINIC JACKSONVILLE · PI FAIRWEATHER, DELISA, WOLFRAM, JOY · 2020 to 2021
$430k
Elucidating the innate and adaptive immune mechanism differences during viral myocarditis between pediatric and adult populations: role of sex, age and hormone statusR21AI180863 · NIAID · UNIVERSITY OF FLORIDA · PI BRUNO, KATELYN ANN · 2024 to 2025
Objective: To evaluate if cardiac troponin values predict poor outcomes in COVID-19 patients across the range of patients of different sex and age. Methods: We examined high-sensitivity cardiac troponin T (hs-cTnT) levels in 1,050 severely ill hospitalized COVID-19 patients who had hs-cTnT data available and participated in the Expanded Access Program for convalescent plasma study during the first wave (April-August 2020) of the COVID-19 pandemic. Results: We observed a continuous relationship between hs-cTnT levels and mortality in hospitalized males and females with COVID-19. This finding was present regardless of sex or age. Conclusion: These data indicate the prognostic ability of hs-cTnT to predict mortality in hospitalized COVID-19 patients across all relevant patient groups. Clinical Trials registration number: NCT04338360.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Cardiac Troponin T Elevation Predicts Mortality in Hospitalized COVID-19 Patients. · full record | OpenQuestion