Evidence map›Paper›PMID 40630548›Full record

ReviewAllergologie select2025

Characteristics of irreversibility in high-resolution computed tomography in chronic hypersensitivity pneumonitis.

Beate Rehbock, Andreas Gschwendtner, Okka W Hamer

Abstract readReview
In one paragraph

Review in Allergologie select, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Beate RehbockInstitute for Lung Imaging and Image Assessment, Potsdam.
Andreas GschwendtnerInstitute of Pathology, Kulmbach Hospital, Kulmbach, and.
Okka W HamerDepartment of Radiology, University Medical Center Regensburg and Caritas St. Maria Lung Clinic, Donaustauf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From a radiological point of view, the statement of irreversibility can only be made with certainty for the signs of irregular reticulation in conjunction with traction bronchiectasis and for honeycomb cysts in the HR-CT morphologically fibrotic phenotype. The HR-CT signs of the inflammatory phenotype can behave differently. Ground-glass nodules always have a reversible potential. In contrast, the underlying pathology of ground-glass opacity can only be assessed over time, as it does not necessarily correlate with inflammation but can also correspond to fine fibrosis. Similarly, air trapping on HR-CT is an important sign of hypersensitivity pneumonitis in both the radiologically inflammatory and fibrotic form. The persistence of air trapping in the inflammatory type over years suggests the possibility of irreversibility of the bronchiolitis in these cases. Whether a higher resolution in HR-CT, such as through photon-counting CT, can lead to clearer differentiation and prediction of reversibility and irreversibility in the future remains to be seen.

Indexed as

air trappingchronic hypersensitivity pneumonitisfibrosisground-glass opacityhigh-resolution computed tomography

Identifiers

PMID40630548
PMCPMC12236190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.