Evidence map›Paper›PMID 40630520›Full record

ArticleResearch square2025

Factors associated with persistent blood stream infection in the Neonatal Intensive Care Unit.

Hanna Lee, Noa Fleiss, Matthew Bizzarro, Richard Feinn, Michelle Rychalsky, Christine Puthawala, David R Peaper, Thomas S Murray

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PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Hanna LeeDepartment of Pediatrics, Yale School of Medicine, New Haven, CT.
Noa FleissDepartment of Pediatrics, Yale School of Medicine, New Haven, CT.ORCID 0000-0002-8161-9643
Matthew BizzarroDepartment of Pediatrics, Yale School of Medicine, New Haven, CT.
Richard FeinnDepartment of Biomedical Sciences, Frank H Netter MD School of Medicine, Quinnipiac University.
Michelle RychalskyDepartment of Pharmacy, Yale New Haven Children's Hospital, New Haven CT.
Christine PuthawalaDepartment of Pediatrics, Yale School of Medicine, New Haven, CT.ORCID 0000-0002-0716-9058
David R PeaperDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT.
Thomas S MurrayDepartment of Pediatrics, Yale School of Medicine, New Haven, CT.ORCID 0000-0002-6829-7213

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study determined factors associated with persistent blood stream infections (BSIs) for infants in the NICU to identify when follow up blood cultures (FUBCs) have increased utility. Study design: Single center study of all infants in a level IV NICU (n=121) with a positive blood culture over a five-year period. Clinical and microbiological variables were examined with bivariate and multi-regression analyses to identify factors associated with persistent BSI, defined as growth of the same organism >48 hours after the index culture. Results: The recovery of Conclusion: In the NICU, both patient and microbial characteristics can inform diagnostic stewardship regarding the need for FUBCs.

Identifiers

PMID40630520
PMCPMC12236895

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.