Evidence map›Paper›PMID 40630463›Full record

ArticleReviews in cardiovascular medicine2025

Association Between the Preoperative Triglyceride-Glucose Index and Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Cardiac Surgery.

Zhen Zhang, Yanwen Jiang, Zhe Luo, Yi Fang, Xiaoqiang Ding, Wuhua Jiang

Abstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhen ZhangDepartment of Nephrology, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.ORCID https://orcid.org/0000-0002-3136-3096
Yanwen JiangDepartment of Nursing, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.
Zhe LuoCardiac Intensive Care Center, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.
Yi FangDepartment of Nephrology, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.
Xiaoqiang DingDepartment of Nephrology, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.
Wuhua JiangDepartment of Nephrology, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.ORCID https://orcid.org/0000-0001-8475-507X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute kidney injury (AKI) is a major complication of cardiac surgery, particularly in patients with pre-existing chronic kidney disease (CKD), who are at higher risk due to their compromised renal function. This study investigated the association between the triglyceride-glucose (TyG) index, a marker of insulin resistance, and postoperative AKI in CKD patients undergoing cardiac surgery to enhance risk stratification and perioperative management. Methods: This retrospective study included 542 patients with impaired renal function (estimated glomerular filtration rate (eGFR) 15-60 mL/min/1.73 m Results: Among the 542 patients, 55.7% developed AKI, and the in-hospital mortality rate was 7.6%. In the multivariate regression analysis, the odds ratio for AKI with each unit increase in LnTyG was 0.43 (95% CI 0.02-8.70, Conclusion: The TyG index is not significantly associated with AKI or prognosis after cardiac surgery in patients with kidney dysfunction. Further studies are needed to elucidate the role of insulin resistance in the pathogenesis of AKI.

Indexed as

acute kidney injurycardiac surgeryinsulin resistancekidney dysfunctionTyG

Identifiers

PMID40630463
PMCPMC12230818

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.