Evidence map›Paper›PMID 40630455›Full record

ArticleReviews in cardiovascular medicine2025

The Impact of Age and Sex on Left Ventricular Function Based on Transthoracic Echocardiograms.

Lu Tang, Rui Wu, Chen Cheng, Zheng Li, Yang Hua, Jin-Yu Sun, Yan-Juan Zhang, Wei Sun, Xiang-Qing Kong

Abstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lu TangDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.ORCID https://orcid.org/0009-0001-7807-614X
Rui WuDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.ORCID https://orcid.org/0009-0002-7543-8907
Chen ChengDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.
Zheng LiDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.
Yang HuaDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.
Jin-Yu SunDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.
Yan-Juan ZhangDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.
Wei SunDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.
Xiang-Qing KongDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to reveal the age- and gender-related differences in left ventricular function among patients with normal cardiac structure. Methods: A retrospective analysis was performed on 10,853 individuals with normal cardiac structures undergoing transthoracic echocardiography (2017-2020). We performed distribution analysis using kernel density estimation with Gaussian kernels and created smooth trajectories based on generalized additive models. Moreover, correlation analysis and multivariable regression were applied to evaluate the impact of age and gender on ventricular function. Results: A weak but statistically significant correlation was found between age and ejection fraction (B-coefficient = -0.077, Conclusion: This study provided the distribution of left ventricular systolic/diastolic function across age decades in males and females and highlighted the clinical importance of monitoring ventricular function even for patients with normal cardiac structure.

Indexed as

agegenderleft ventricular diastolic functionleft ventricular systolic functiontransthoracic echocardiogram

Identifiers

PMID40630455
PMCPMC12230827

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.