ArticleReviews in cardiovascular medicine2025
Impact of Arterial Stiffness on In-Stent Restenosis in the Era of Drug-Eluting Stents.
Article in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Association of Arterial Stiffness (Brachial-Ankle Pulse Wave Velocity) with Angiographic Outcomes After Drug-Eluting Stent Implantation: A Retrospective Lesion-Level Cohort Study.Journal of clinical medicine · 2026Article
- Deployable 3D-Printed Vascular Stent with Surface-Catalysed Endogenous Nitric Oxide Generation.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Association of estimated pulse wave velocity with outcomes following drug-coated balloon therapy in elderly coronary artery disease patients.Frontiers in cardiovascular medicine · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In the era of drug-eluting stents (DESs), few studies have explored the association between arterial stiffness and the risk of in-stent restenosis (ISR). Methods: Pulse pressure and pulse pressure index (PPI), which are noninvasive measures of arterial stiffness, were measured before percutaneous coronary interventions (PCI). PPI is the ratio of pulse pressure to systolic blood pressure. ISR was defined based on the angiographic evidence of ≥50% stenosis within the previously stented segment. Logistic regression was used to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for ISR. Results: A total of 644 patients were collected, including 72 patients in the ISR group. Pulse pressure and PPI were significantly higher in the ISR group (ISR vs no ISR: pulse pressure, 58.5 ± 16.3 vs 53.1 ± 13.7 mmHg [ Conclusions: Arterial stiffness denoted by high pulse pressure and PPI is a predictive factor for ISR. A pre-PCI wide pulse pressure could potentially serve as a marker of risk, as well as a potential target for future therapies. Clinical trial registration: ChiCTR2000039901, https://www.chictr.org.cn/showproj.html?proj=51063.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.