Evidence map›Paper›PMID 40630381›Full record

ArticleERJ open research2025

Long-term exercise capacity in paediatric cystic fibrosis: a modern era perspective.

René Gaupmann, Laura Stöger, Klara Schmidthaler, Bianca Pauger, Brigitte Mersi, Alexandra Graf, Zsolt Szépfalusi, Sabine Renner, Eleonora Dehlink, Saskia Gruber

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

René GaupmannDepartment of Paediatrics, Division of Paediatric Pulmonology, Allergy and Endocrinology, Medical University of Vienna, Vienna, Austria.
Laura StögerDepartment of Paediatrics, Division of Paediatric Pulmonology, Allergy and Endocrinology, Medical University of Vienna, Vienna, Austria.
Klara SchmidthalerDepartment of Paediatrics, Division of Paediatric Pulmonology, Allergy and Endocrinology, Medical University of Vienna, Vienna, Austria.
Bianca PaugerDepartment of Paediatrics, Division of Paediatric Pulmonology, Allergy and Endocrinology, Medical University of Vienna, Vienna, Austria.
Brigitte MersiDepartment of Paediatrics, Division of Paediatric Pulmonology, Allergy and Endocrinology, Medical University of Vienna, Vienna, Austria.
Alexandra GrafInstitute for Medical Statistics, Centre for Medical Data Science, Medical University of Vienna, Vienna, Austria.
Zsolt SzépfalusiDepartment of Paediatrics, Division of Paediatric Pulmonology, Allergy and Endocrinology, Medical University of Vienna, Vienna, Austria.
Sabine RennerDepartment of Paediatrics, Division of Paediatric Pulmonology, Allergy and Endocrinology, Medical University of Vienna, Vienna, Austria.
Eleonora DehlinkDepartment of Paediatrics, Division of Paediatric Pulmonology, Allergy and Endocrinology, Medical University of Vienna, Vienna, Austria.
Saskia GruberDepartment of Paediatrics, Division of Paediatric Pulmonology, Allergy and Endocrinology, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Maintaining good cardiopulmonary fitness is crucial for global health in cystic fibrosis (CF), but there is limited knowledge about the longitudinal evolution of fitness measures at young ages, particularly with recent therapeutic advances. We investigated trends in exercise test outcomes in young people with CF and how they are influenced by elexacaftor, tezacaftor and ivacaftor (ETI) and the coronavirus disease 2019 (COVID-19) pandemic. Methods: 70 young people with CF (12-20 years old) were included in this retrospective observational single-centre study. We reviewed 177 symptom-limited surveillance cardiopulmonary exercise tests (CPETs) conducted on a cycle ergometer between 2010 and 2024. Longitudinal trends in peak oxygen uptake ( Results: In ETI-naive people with CF, Conclusion: The longitudinal trend in

Identifiers

PMID40630381
PMCPMC12230750

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.