Evidence map›Paper›PMID 40630361›Full record

ArticleCureus2025

Breaking the Silence: A Case for Early Intervention in Profound Adolescent Hearing Loss.

Alejandra C Vargas, Rommel F Portilla, Andrea G Ramirez, Isis X Muñoz, Melanie Caballero Garcia, Maria Guaman, Carlos Valladares

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alejandra C VargasDepartment of General Medicine, Chanchajalla Primary Health Care Facility, Ica, PER.
Rommel F PortillaSchool of Medicine, Universidad de las Américas, Quito, ECU.
Andrea G RamirezFacultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Lima, PER.
Isis X MuñozFaculty of Medicine, National Autonomous University of Mexico, Mexico City, MEX.
Melanie Caballero GarciaDepartment of General Medicine, San Martín de Porres University, Lima, PER.
Maria GuamanFaculty of Medicine, Universidad Católica Boliviana San Pablo, Santa Cruz de la Sierra, BOL.
Carlos ValladaresDepartment of Internal Medicine, Community Medical Center, Toms River, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive unilateral hearing loss (PUHL) in adolescents is uncommon and presents diagnostic challenges due to its varied etiologies, including infections, ototoxicity, congenital anomalies, and autoimmune conditions, though many cases remain idiopathic. We report a 16-year-old male with a history of COVID-19, dengue at age 14, and recurrent headaches, who developed left-sided hearing loss progressing to profound unilateral deafness. Audiometry confirmed sensorineural hearing loss (SNHL) of 97 dB HL in the left ear and 35 dB HL in the right. Despite multiple evaluations, no definitive etiology was identified. Differential diagnoses included post-viral sequelae, congenital anomalies (e.g., Mondini dysplasia), and nasal obstruction, though insurance limitations restricted further testing. The patient discontinued hearing aid use due to limited benefit and experienced social withdrawal, impacting both academic performance and overall well-being. This case underscores the importance of early recognition and a systematic, multidisciplinary approach to PUHL, including imaging and genetic testing, given its potential impact on social development, mental health, and long-term outcomes.

Indexed as

adolescentsdiagnostic limitationspost-viral hearing lossprogressive unilateral hearing losssocial withdrawal

Identifiers

PMID40630361
PMCPMC12237498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.