A Refractory, Gas-Predominant Subgroup of Irritable Bowel Syndrome Markedly Improved With Relatively Long-Term Paroxetine Treatment: A Preliminary Study.

Kazunori Mine, Yusuke Murata, Minoru Fujino, Takehiko Fujino, Munechika Enjoji

Abstract read

In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kazunori MineFaculty of Psychosomatic Medicine, BOOCS Clinic Fukuoka, Fukuoka, JPN.

Yusuke MurataDepartment of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, JPN.

Minoru FujinoFaculty of Internal Medicine, BOOCS Clinic Fukuoka, Fukuoka, JPN.

Takehiko FujinoFaculty of Internal Medicine, BOOCS Clinic Fukuoka, Fukuoka, JPN.

Munechika EnjojiDepartment of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The intestinal-gas symptoms of irritable bowel syndrome (IBS) are particularly bothersome and refractory. In our Japanese clinical practice, we often experience IBS patients with severe complaints of excess 'flatulence' or 'rumbling' as well as bloating, and have considerable difficulty in treating them. However, few studies have been reported on this subgroup of IBS for whom intestinal-gas symptom is the most bothersome

Indexed as

amitriptylineflatulencefunctional gastrointestinal disordergas symptomirritable bowel syndromeparoxetinepharmacotherapy

Identifiers

PMID40630356

DOI10.7759/cureus.85494

PMCPMC12234837

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.