ArticleCureus2025
Minimally Invasive Mitral Valve Replacement in a Patient With a Giant Left Atrium.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A giant left atrium (GLA) is a challenging manifestation of advanced mitral valve disease, often necessitating mitral valve surgery via median sternotomy due to the anatomical distortion it causes. We present the case of a 50-year-old male patient with New York Heart Association (NYHA) class IV symptoms secondary to severe mitral regurgitation, found to have a left atrial diameter of 17.1 cm, to our knowledge, one of the largest ever reported. After declining sternotomy, the patient underwent successful minimally invasive mitral valve replacement. Despite significant anatomical challenges, the procedure was completed uneventfully through careful preoperative planning and specialized intraoperative techniques. While sternotomy remains standard in such complex presentations, advances in imaging, instrumentation, and surgical expertise are redefining procedural boundaries. This case demonstrates that minimally invasive mitral valve replacement can be safe, feasible, and effective even in patients with extreme atrial enlargement when performed by experienced teams.
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