Evidence map›Paper›PMID 40630308›Full record

ArticleKidney international reports2025

The Clinicopathologic Characteristics of Recurrent Lupus Nephritis Post-Transplant Using Surveillance and Indication Biopsies.

Maria Lourdes Gonzalez Suarez, Wen Jiqiu, Andrea G Kattah, Loren P Herrera Hernandez, Carrie A Schinstock, Mireille El Ters, Leticia Rolon, Mary E Fidler, Samih H Nasr, Sanjeev Z Sethi and 14 more

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Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Maria Lourdes Gonzalez SuarezDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Wen JiqiuInstitute of Transplantation Medicine, The Second Affiliated Hospital of Guangxi Medical University Guangxi Clinical Research Center for Organ Transplantation, Guangxi Key Laboratory of Organ Donation and Transplantation, Nanning, China.
Andrea G KattahDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Loren P Herrera HernandezDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Carrie A SchinstockDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Mireille El TersDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Leticia RolonDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Mary E FidlerDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Samih H NasrDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Sanjeev Z SethiDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Martin MaiDivision of Nephrology and Hypertension, Mayo Clinic, Jacksonville, Florida, USA.
Hasan KhamashDivision of Nephrology and Hypertension, Mayo Clinic, Scottsdale, Arizona, USA.
Mark D StegallDepartment of Transplant Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Sam T AlbadriDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Ali Duarte-GarciaDivision of Rheumatology and the Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA.
Maxwell SmithDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, Arizona, USA.
Hatem AmerDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Lynn D CornellDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Ladan ZandDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Timucin TanerDepartment of Transplant Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Ingeborg M BajemaDepartment of Pathology and Medical Biology, University Medical Center Groningen, and University of Groningen, The Netherlands.
Fernando C FervenzaDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Mariam P AlexanderDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Andrew J BentallDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The incidence of recurrent lupus nephritis (RLN) after kidney transplantation (KTx) varies with higher rates of RLN reported in surveillance biopsy-based studies (vs. clinically indicated biopsies). Methods: We present a multisite retrospective study evaluating surveillance and clinically indicated biopsies in 209 first KTx recipients who had native lupus disease. Results: Of the 112 patients with satisfactory material for comprehensive histology, RLN was observed in 40 (35.7%). We describe the pathology of histologic RLN (HRLN; 40%) and clinical RLN (CRLN; 60%). African Americans had the highest recurrence rate (48.3%) of whom 50% had CRLN. HRLN was noted as early as 18 days, with early diagnosis (< 3 months of follow-up time) using surveillance biopsies. Mesangioproliferative pattern of glomerular injury ( Conclusion: Our study demonstrates that RLN is frequent and may be clinically quiescent. Sequential biopsy evaluation provided an opportunity to study the natural evolution of the disease.

Indexed as

clinical recurrencegrafthistologic recurrencelupus nephritisrenal transplantation

Identifiers

PMID40630308
PMCPMC12231029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.