ArticleKidney international reports2025
Spectrum of Kidney Pathology in Patients With Syphilis.
Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Membranous nephropathy and hepatitis secondary to syphilis: a case report and literature review.CEN case reports · 2026Review
- Membranous Nephropathy Secondary to Syphilis.Case reports in nephrology · 2026Article
- Clinical characteristics and survival among HIV-infected people undergoing maintenance hemodialysis: a comparative study from Shanghai, China.BMC infectious diseases · 2025Article
- Antigens in membranous nephropathy: discovery and clinical implications.Nature reviews. Nephrology · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Syphilis has been associated with multiple kidney diseases, primarily studied within small series. A large cohort of patients with active syphilis who underwent kidney biopsy were examined to evaluate the histopathologic spectrum and clinicopathologic features of the disease. Methods: Patients with syphilis who underwent a native kidney biopsy were identified from renal pathology archives at Arkana Laboratories. Patients were identified through a clinical history of active syphilis in medical records and/or positive serologic testing (rapid plasma reagin, venereal disease research laboratory, or antitreponemal antibodies). Results: A total of 102 patients with syphilis who underwent kidney biopsy were identified. The mean age was 41.0 ± 14.0 years with male predominance (87.3%). The majority presented with acute kidney injury (AKI) with a mean creatinine of 4.7 ± 4.0 mg/dl. Coinfections, including HIV, hepatitis B virus, and hepatitis C virus were common. The most common disease states included membranous nephropathy (MN, Conclusion: A spectrum of kidney pathology diagnoses is seen in patients with syphilis, with the majority of patients presenting with AKI. Coinfections, and pathology related to coinfections, were common.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.