ArticleLaryngoscope investigative otolaryngology2025
A Nationwide Review of Pediatric Total Thyroidectomy and Lobectomy Outcomes.
Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Risk factors for postoperative recurrence of thyroid cancer patients in children, adolescents, and young adults.Translational pediatrics · 2026Article
- A Nationwide Review of Pediatric Total Thyroidectomy and Lobectomy Outcomes.Laryngoscope investigative otolaryngology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Pediatric thyroid cancer (PTC) exhibits unique differences in pathophysiology, clinical presentation, and outcomes compared to adult thyroid cancer. In 2015, the American Thyroid Association released inaugural recommendations for pediatric thyroid nodules and cancer management. Significant increases in thyroid lobectomy for PTC have since been reported. This study represents the largest nationwide analysis comparing characteristics and clinical outcomes in pediatric total thyroidectomy (TT) and thyroid lobectomy (TL). Methods: A retrospective cross-sectional analysis of the Nationwide Readmissions Database (NRD) from 2010 to 2019 was performed. The study population included pediatric (< 18 years) patients undergoing TT and TL. Thyroidectomy procedures were classified using ICD-9-CM and ICD-10-PCS procedure codes, which do not distinguish between initial (primary) lobectomy and completion thyroidectomy. Due to coding limitations, the TL group includes both initial and completion lobectomies. Data were analyzed in September 2022. Primary outcomes included complication rates, hospitalization length of stay (LOS), costs, and 30-day readmission rates. Results: 3793 patients were included. 72.4% underwent TT, and 27.6% had TL. Median age was 15; 78% were female. Surgical indications included thyroid cancer (43%), toxic thyroid disease (28%), benign disease (24%), and MEN 2A/B (4%). Risk of postoperative hypocalcemia was significantly increased in TT (25%) compared to TL (11%) ( Conclusion: This study represents the largest nationwide analysis comparing pediatric total thyroidectomy and lobectomy to date, revealing TL's association with reduced postoperative hypocalcemia, LOS, cost, and readmission risk. As pediatric thyroid management patterns continue to change, this study provides critical information to guide management and decision-making, improving patient outcomes. Level of Evidence: III.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.