ArticleFrontiers in nutrition2025
Maternal dietary iron intake during pregnancy has a potential effect on the neonate gut microbiota profile.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Iron is an essential nutrient during pregnancy and may influence the early development of the neonatal gut microbiota. This study aimed to investigate the association between maternal dietary iron intake during pregnancy and the gut microbiota (GM) characteristics of both the mother and neonate in a well-characterized cohort. Methods: Ninety-five mother-neonate dyads were included in this study. Mothers completed a food frequency questionnaire (FFQ) providing estimates of dietary iron intake during pregnancy, and participants were categorized into higher (≥ median) or lower (< median) groups of maternal dietary iron intake. Fecal samples were collected from mothers (third trimester) and from neonates, and assessed via 16S rRNA amplicon sequencing. Differences in diversity and abundance of GM were compared between groups. Results: There was no difference in profile or diversity in maternal samples however, neonatal samples indicated greater diversity of GM in infants of mothers with higher intakes of iron (Shannon Conclusion: Adequate dietary iron intake during pregnancy may promote beneficial bacterial colonization and increase the biodiversity of the neonate GM.
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