Evidence map›Paper›PMID 40630159›Full record

ArticleJournal of arrhythmia2025

Differing impacts of cardiac implantable electronic device leads on tricuspid regurgitation.

Sophie A Leon, Melissa Austin, Nayeem Nasher, Daler Rahimov, Faizaan Siddique, Chitra Parikh, Danial Ahmad, Vakhtang Tchantchaleishvili, Behzad B Pavri

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Molecular Mechanisms of Cardiac Adaptation After Device Deployment.Journal of cardiovascular development and disease · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sophie A LeonDepartment of Cardiac Surgery Thomas Jefferson University Hospital Philadelphia Pennsylvania USA.
Melissa AustinDepartment of Cardiac Surgery Thomas Jefferson University Hospital Philadelphia Pennsylvania USA.
Nayeem NasherDepartment of Cardiac Surgery Thomas Jefferson University Hospital Philadelphia Pennsylvania USA.
Daler RahimovDepartment of Cardiac Surgery Thomas Jefferson University Hospital Philadelphia Pennsylvania USA.ORCID https://orcid.org/0009-0004-8055-6101
Faizaan SiddiqueDepartment of Cardiac Surgery Thomas Jefferson University Hospital Philadelphia Pennsylvania USA.
Chitra ParikhDepartment of Cardiac Surgery Thomas Jefferson University Hospital Philadelphia Pennsylvania USA.
Danial AhmadDepartment of Cardiac Surgery Thomas Jefferson University Hospital Philadelphia Pennsylvania USA.
Vakhtang TchantchaleishviliDepartment of Cardiac Surgery Thomas Jefferson University Hospital Philadelphia Pennsylvania USA.
Behzad B PavriDivision of Cardiology, Department of Medicine Thomas Jefferson University Hospital Philadelphia Pennsylvania USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Placement of cardiac implantable electronic devices (CIED) with leads that traverse the tricuspid valve is thought to contribute to tricuspid regurgitation (TR). However, there are relatively limited data comparing the impact of different CIED lead types on the incidence and progression of TR. This study sought to quantify the change in TR severity following implantation of CIEDs with different lead types. Methods: Patient data were collected on individuals with implantable cardioverter defibrillators (ICD), right ventricular-paced pacemakers (RV-PM), and His bundle-paced pacemakers (His-PM) placed by a single provider at a single institution between 2016 and 2019. Patients with extravascular CIED placement or with existing devices undergoing upgrade procedures were excluded. Severity of TR after CIED implantation was compared to baseline TR. Results: A total of 97 patients receiving CIEDs were analyzed, including 63 with RV-PMs, 23 with ICDs, and 11 with His-PMs. Median patient age was 72 [interquartile range (IQR) 63-81] years, and 44% of patients were female. Echocardiograms were obtained a median of 20 [4-91] days before CIED implantation and 31 [17.9-43.0] months following implantation. Baseline TR grade was comparable between groups ( Conclusion: The effect of CIED leads on TR represents a spectrum related to the type of lead traversing the tricuspid valve.

Indexed as

defibrillatorhis bundle pacemakerpacemakertricuspid regurgitation

Identifiers

PMID40630159
PMCPMC12234372

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.