Evidence map›Paper›PMID 40630021›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2025

Development of Artificial Intelligence-Assisted Lumbar and Femoral BMD Estimation System Using Anteroposterior Lumbar X-Ray Images.

Toru Moro, Noriko Yoshimura, Taku Saito, Hiroyuki Oka, Sigeyuki Muraki, Toshiko Iidaka, Takeyuki Tanaka, Kumiko Ono, Hisatoshi Ishikura, Naoya Wada and 3 more

Abstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Toru MoroDivision of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-7448-5237
Noriko YoshimuraDepartment of Prevention Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, The University of Tokyo Hospital, Tokyo, Japan.
Taku SaitoSensory and Motor System Medicine, Faculty of Medicine Surgical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroyuki OkaSensory and Motor System Medicine, Faculty of Medicine Surgical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Sigeyuki MurakiSensory and Motor System Medicine, Faculty of Medicine Surgical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Toshiko IidakaSensory and Motor System Medicine, Faculty of Medicine Surgical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Takeyuki TanakaSensory and Motor System Medicine, Faculty of Medicine Surgical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kumiko OnoSensory and Motor System Medicine, Faculty of Medicine Surgical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hisatoshi IshikuraSensory and Motor System Medicine, Faculty of Medicine Surgical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Naoya WadaAdvanced Technology Research Institute, Corporate R&D Group, KYOCERA Corporation, Kawasaki, Kanagawa, Japan.
Kenichi WatanabeDivision of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Masayuki KyomotoDivision of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Sakae TanakaSensory and Motor System Medicine, Faculty of Medicine Surgical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Funding

The study was supported by the Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (B) (20H03798).
6 · The paper itself

Abstract

The early detection and treatment of osteoporosis and prevention of fragility fractures are urgent societal issues. We developed an artificial intelligence-assisted diagnostic system that estimated not only lumbar bone mineral density but also femoral bone mineral density from anteroposterior lumbar X-ray images. We evaluated the performance of lumbar and femoral bone mineral density estimations and the osteoporosis classification accuracy of an artificial intelligence-assisted diagnostic system using lumbar X-ray images from a population-based cohort. The artificial neural network consisted of a deep neural network for estimating lumbar and femoral bone mineral density values and classifying lumbar X-ray images into osteoporosis categories. The deep neural network was built by training dual-energy X-ray absorptiometry-derived lumbar and femoral bone mineral density values as the ground truth of the training data and preprocessed X-ray images. Five-fold cross-validation was performed to evaluate the accuracy of the estimated BMD. A total of 1454 X-ray images from 1454 participants were analyzed using the artificial neural network. For the bone mineral density estimation performance, the mean absolute errors were 0.076 g/cm

Indexed as

Artificial IntelligenceBone DensityFemurLumbar VertebraeOsteoporosisAbsorptiometry, PhotonAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeural Networks, Computerartificial intelligencebone densitybone mineral densitydeep learningosteopeniaosteoporosis

Identifiers

PMID40630021
PMCPMC12329632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.