Evidence map›Paper›PMID 40629792›Full record

ArticleAnnals of cardiac anaesthesia2025

Intraoperative Plasma Exchange for Sensitized Lung Transplantation Candidate Leads to Significant Perioperative Coagulopathy.

Luke Landolt, Joseph C Goldstein, William Weir, Mindaugas Rackauskas, Joseph AbuRahma

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In one paragraph

Article in Annals of cardiac anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luke LandoltDepartment of Anesthesiology, University of Florida College of Medicine, Gainesville, FL, USA.
Joseph C GoldsteinDepartment of Anesthesiology, North Florida/South Georgia Veterans Health System and University of Florida College of Medicine, Gainesville, FL, USA.
William WeirDepartment of Surgery, Division of Thoracic Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
Mindaugas RackauskasDepartment of Surgery, Division of Thoracic Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
Joseph AbuRahmaDepartment of Anesthesiology, University of Florida College of Medicine, Gainesville, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractSensitized lung transplantation recipients are at an increased risk for complications. Therapies such as plasma exchange (PLEX) exist to lessen the antibody burden in hopes of mitigating acute and chronic complications. Although the use of PLEX has been shown to be an effective immunomodulation for many diseases, its benefit in lung transplantation has been debated, and the fear of PLEX-induced coagulopathy has curtailed its use more broadly. Although the type of fluid used for exchange can determine the severity of coagulopathy, even the use of fresh frozen plasma (FFP) can disrupt the coagulation cascade. We present the case of severe perioperative coagulopathy following PLEX with FFP during bilateral lung transplantation.

Indexed as

Blood Coagulation DisordersIntraoperative CareIntraoperative ComplicationsLung TransplantationPlasma ExchangeHumansBilateral orthotopic lung transplantationcoagulopathyextracorporeal membrane oxygenationhuman leukocyte antigenplasma exchange

Identifiers

PMID40629792
PMCPMC12324751

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.