Evidence map›Paper›PMID 40629650›Full record

ArticleMedicine2025

Coexisting tubal pregnancy and intrauterine pregnancy during a natural pregnancy, first diagnosed via ultrasonography: A case report.

Lin Pan, Shanshan Wang, Yan Huang, Ting Feng, Huaguo Shao

Abstract readCase Reports
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lin PanDepartment of Ultrasound, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou City, Zhejiang Province, China.
Shanshan WangDepartment of Ultrasound, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou City, Zhejiang Province, China.
Yan HuangDepartment of Ultrasound, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou City, Zhejiang Province, China.
Ting FengDepartment of Ultrasound, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou City, Zhejiang Province, China.
Huaguo ShaoInstitute of Hepatology and Epidemiology, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou City, Zhejiang Province, China.ORCID 0009-0000-7633-6879

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleThe coexistence of intrauterine and extrauterine pregnancies is termed heterotopic pregnancy (HP). Most reported cases of HP occur after assisted reproductive technology, and HP in a natural pregnancy (NP) is very rare, often discovered intraoperatively. HP is a significant challenge for obstetricians, gynecologists, and sonographers. PATIENT CONCERNS: A 30-year-old nulliparous woman presented to the emergency department of a local tertiary hospital on day 66 of amenorrhea with abdominal pain, nausea, and vomiting without an obvious cause. DIAGNOSES: Transabdominal gynecological ultrasonography revealed coexisting left ectopic pregnancy (EP) and intrauterine pregnancy (IP) in the NP, both with measurable fetal heart activity. In addition, abdominal fluid and extensive pelvic hematoma were observed.

interventionsGiven a ruptured EP with hemorrhage, the obstetrician-gynecologist performed an emergency surgery, finding approximately 500 mL of blood and blood clots in the abdominal and pelvic cavities. The left tubal ampullary segment was dilated and thickened, with a visible rupture and active bleeding. Therefore, the left fallopian tube was resected, and IP was managed with therapy. OUTCOMES: The patient recovered well postoperatively and delivered a male infant by cesarean section at full term. LESSONS: The presence of IP does not exclude the coexistence of EP, even in NP. Although HP is rare and the symptoms of EP may not be obvious, sometimes masked by IP, obstetricians, gynecologists, and sonographers must remain vigilant in this regard to reduce the rate of missed diagnoses, provide early intervention, and safeguard the health of the pregnant woman and fetus.

Indexed as

Pregnancy, EctopicPregnancy, HeterotopicPregnancy, TubalAdultFemaleHumansPregnancyUltrasonographyheterotopic pregnancyintrauterine pregnancynatural pregnancytubal pregnancyultrasonography

Identifiers

PMID40629650
PMCPMC12237362

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.