Evidence map›Paper›PMID 40629644›Full record

ArticleMedicine2025

A case of psittacosis chlamydia pneumonia in patients with anti-infection drugs analysis and pharmaceutical care.

Hui He, Di Shen

Abstract readCase Reports
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

2 authors.

Hui HeThe People's Hospital of Renshou County & The Second People's Hospital of Meishan City, Meishan, Sichuan Province, China.
Di ShenWenshan Prefecture Dermatology Prevention and Treatment Institute (Wenshan Prefecture Dermatology Specialist Hospital), Wenshan, Yunnan Province, China.ORCID 0009-0002-9971-2667

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationalePsittacosis pneumonia, caused by Chlamydia psittaci, is an underdiagnosed zoonotic infection. This case aims to demonstrate the efficacy of azithromycin as an alternative therapy and highlight the value of clinical pharmacists in managing drug-resistant infections. PATIENT CONCERNS: A 56-year-old female poultry farmer presented with persistent high fever (38.5-39.0°C), chills, body aches, and fatigue for 2 weeks. Initial outpatient treatment with unspecified oral medication provided no relief. DIAGNOSES: Metagenomic next-generation sequencing of bronchoalveolar lavage fluid confirmed C psittaci and rhinovirus co-infection, explaining treatment failure with empirical piperacillin-tazobactam for presumed bacterial pneumonia.

interventionsAfter pathogen identification, intravenous azithromycin monotherapy (4.5 g total dose) was initiated. Clinical pharmacists collaborated on regimen design, monitored for QTc prolongation/electrolyte imbalances, and ensured safety during the 12-day course. OUTCOMES: Fever resolved within 48 hours; all symptoms improved by day 6. Follow-up computed tomography showed significant resolution of lung consolidation. The patient was discharged on day 11 with oral azithromycin continuation. LESSONS: Azithromycin is effective as second-line therapy for severe psittacosis when tetracyclines are inaccessible. Metagenomic next-generation sequencing enables rapid diagnosis of atypical pathogens, while pharmacist-led pharmaceutical care optimizes antimicrobial selection and safety monitoring, particularly for cardiotoxic drugs.

Indexed as

Anti-Bacterial AgentsAzithromycinChlamydophila psittaciPneumonia, BacterialPsittacosisFemaleHumansMiddle AgedAnti-Bacterial AgentsAzithromycinanti-infective treatmentclinical pharmacistspharmaceutical care

Identifiers

PMID40629644
PMCPMC12237299

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