Observational studyMedicine2025
Inspiratory muscle training after atrial fibrillation catheter ablation: A pilot study.
Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
Abstract
Atrial fibrillation management is challenging, and traditional cardiac rehabilitation often overlooks respiratory issues. We aimed to evaluate the safety and efficacy of cardiac rehabilitation with inspiratory muscle training to enhance respiratory and cardiac functions after atrial fibrillation catheter ablation. This prospective, single-center observational study, conducted at the University of Tokyo Hospital between February 2019 and January 2020, included 5 men (average age 68.4 ± 2.58 years) who underwent initial ablation for symptomatic paroxysmal (n = 1) or non-paroxysmal (n = 4) atrial fibrillation. The participants underwent inspiratory muscle training alongside standard cardiac rehabilitation (intensity: 20% of the maximal inspiratory pressure, adjusted weekly). The pre- and post-intervention ejection fraction, left atrial volume index, and brain natriuretic peptide levels were evaluated. Inspiratory muscle training integration was associated with improvements in respiratory muscle strength and pulmonary function. The average ejection fraction improved from 62.0% to 64.4%, the left atrial volume index decreased from 39.4 mL/m2 to 27.0 mL/m2, and brain natriuretic peptide levels reduced from 112.28 pg/mL to 20.98 pg/mL. The anaerobic threshold increased from a mean of 12.3 to 14.2, and the mean peak oxygen uptake increased from 16.72 mL/kg/min to 18.12 mL/kg/min. Over a 4-year follow-up, atrial fibrillation recurrence was observed in only 1 of the 5 patients. Inspiratory muscle training, when integrated with cardiac rehabilitation, could potentially improve respiratory and cardiac function in patients with post-atrial fibrillation ablation and may help reduce the likelihood of atrial fibrillation recurrence. This pilot study supports the potential of inspiratory muscle training in enhancing standard rehabilitation protocols, warranting further investigation in larger randomized trials to substantiate these findings and explore long-term benefits.
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