ReviewActa epileptologica2025
From the different pathogenesis of epileptogenesis: vitamins as an adjunctive treatment for epilepsy.
Review in Acta epileptologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Selected Molecular Targets for Counteracting Epileptogenesis: What Do We Know About Its Effective Inhibition?Current issues in molecular biology · 2026Review
- The Role of Antioxidants in the Connection Between Microbiota, Neuroinflammation and Epilepsy.Biomedicines · 2026Review
- Nutrients and bioactive compounds as modifiers of neurodegenerative trajectories: molecular mechanisms, translational barriers, and precision nutrition.Frontiers in nutrition · 2026Review
- Vitamin D is involved in regulating limbic epileptogenesis.Brain communications · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Vitamins play an essential role in the maintenance of normal physiological functions of the human body. In recent years, the use of vitamins as an adjunctive treatment for epilepsy has attracted increasing interest academically. There is a substantial body of evidence indicating that vitamin supplementation could contribute to the treatment and prevention of epilepsy. This review discusses the pathogenesis of epilepsy associated with ten vitamins from five perspectives, namely, inflammatory signaling pathways, excitotoxicity, oxidative stress, neuroprotection, and the blood-brain barrier, and explores the relationships between the gut microbiota and vitamins in epileptic disorders with a focus on summarizing the antiepileptic effects of vitamin D and vitamin E. In addition, we discuss the effects of antiseizure medications on vitamins. This review aims to provide a more comprehensive view of the use of vitamins as an adjunctive therapy in epilepsy.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.