Evidence map›Paper›PMID 40629465›Full record

SynthesisJournal of orthopaedic surgery and research2025

Economic evaluation of robotic-assisted versus manual unicompartmental knee arthroplasty: a systematic review of Markov models and clinical studies.

Sadra Mohebbi, Yashar Khani, Amirhossein Amiri, Amirreza Arab, Marzieh Mahmoudi Zarandi, Zeinab Imani, Amir Dadgostar, Amir Mehrvar

Abstract readSystematic ReviewComparative Study
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sadra MohebbiSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Yashar KhaniSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Amirhossein AmiriSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Amirreza ArabSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Marzieh Mahmoudi ZarandiSports and Exercise Medicine Resident, Tehran University of Medical Sciences, Tehran, Iran.
Zeinab ImaniCenter of Orthopedic Trans-Disciplinary Applied Research (COTAR), Tehran University of Medical Sciences, Tehran, Iran.
Amir DadgostarFaculty of Medicine, Islamic Azad University, Tehran, Iran.
Amir MehrvarClinical Research Development Units, Taleghani Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran. drmehrvar@sbmu.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis systematic review aimed to compare the cost-effectiveness of robotic-assisted unicompartmental knee arthroplasty (rUKA) with manual UKA (mUKA) for patients who have isolated unicompartmental knee osteoarthritis (OA).

methodsA systematic review was conducted following PRISMA guidelines, searching databases including PubMed, Scopus, Embase, and Web of Science up to January 2025. Studies comparing the cost-effectiveness of rUKA and mUKA, including cohort studies, case-control studies, clinical trials, and Markov models, were eligible for inclusion in this study. There were no restrictions. Independent reviewers conducted the screening, data extraction, and quality assessment of the studies, and any resolved conflicts were discussed and referred to the corresponding reviewer for resolution. The National Institute of Health (NIH) tools were utilized for quality assessment of the cohort studies and RCTs. Qualitative synthesis was performed due to methodological heterogeneity. Also, the protocol of this study was registered prospectively on the PROSPERO with registration number CRD420250645008.

resultsEight studies, including four Markov and four non-Markov from the US and UK, were included in the study. The rUKA procedure showed higher initial costs but improved quality-adjusted life years (QALYs) and lower revision rates compared to mUKA. Incremental cost-effectiveness ratios (ICERs) ranged from £1,238 (approximately $1672) to $47,180 per QALY, consistently below country-specific thresholds, indicating cost-effectiveness, particularly in high-volume centers. Long-term follow-up further supported rUKA, with notable cost savings.

conclusionsDespite higher upfront costs, rUKA appears to be cost-effective compared to mUKA, driven by reduced revisions and enhanced outcomes, especially in high-volume settings and over extended follow-up periods.

Indexed as

Arthroplasty, Replacement, KneeCost-Benefit AnalysisOsteoarthritis, KneeRobotic Surgical ProceduresHumansMarkov ChainsCost-effectivenessRobotic assistanceUnicompartmental knee arthroplasty

Identifiers

PMID40629465
PMCPMC12235986

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.