Evidence map›Paper›PMID 40629462›Full record

ArticleBMC psychology2025

Effectiveness of adapted self-help plus (SH+) to reduce psychological distress among university students in Indonesia (APRESIASI): protocol of a randomized controlled trial.

Dhini Andriani, Fredrick D Purba, Anke B Witteveen, Neily Zakiyah, Marit Sijbrandij

Abstract readClinical Trial Protocol
In one paragraph

Article in BMC psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dhini AndrianiDepartment of Clinical, Neuro- and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. d.andriani@vu.nl.ORCID http://orcid.org/0000-0002-6718-5789
Fredrick D PurbaDepartment of Psychology, Faculty of Psychology, Universitas Padjadjaran, Jatinangor, Indonesia.ORCID http://orcid.org/0000-0002-7336-3043
Anke B WitteveenDepartment of Clinical, Neuro- and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.ORCID http://orcid.org/0000-0002-9636-7522
Neily ZakiyahDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, Indonesia.ORCID http://orcid.org/0000-0002-9630-5567
Marit SijbrandijDepartment of Clinical, Neuro- and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.ORCID http://orcid.org/0000-0001-5430-9810

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUniversity students in Indonesia are exposed to stressors such as high academic task load, financial strains, and relationship problems. Therefore, they are at risk of developing symptoms of common mental disorders, such as depression and anxiety (i.e., psychological distress). However, there is a gap between the number of mental health professionals and the number of students in need of a psychological intervention. Self-Help Plus (SH+), a guided group-based stress management intervention developed by the WHO, was adapted to the population and context to address barriers in accessing mental health care among students in Indonesia. The aim of the APRESIASI study is to assess the effectiveness and cost-effectiveness of SH + in reducing psychological distress among university students in Indonesia.

methodsThe SH + intervention will be tested in a pragmatic superior randomized controlled trial (RCT) with two parallel arms. SH + will be tested among Indonesian university students with symptoms of psychological distress (Patient Health Questionnaire-9; PHQ-9 ≥ 5.5 < 20). The participants (n = 296) will be randomized into either the intervention group that receives SH + with enhanced care as usual (ECAU), or into the ECAU only with a 1:1 allocation ratio. The primary outcome is the reduction in psychological distress assessed with the Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS) at three-month follow-up. The secondary outcomes are symptoms of depression, anxiety, perceived stress, functioning, resilience, quality of life, identified problems, treatment acceptability, and cost-effectiveness. DISCUSSION: To our knowledge, SH + is the first a transdiagnostic, face-to-face, and group-based intervention to be tested for its effectiveness in reducing psychological distress in Indonesia. If shown to be effective, SH + has the potential to be scaled up across university settings.

trial registrationISRCTN15761598, 14/07/2023.

Indexed as

Psychological DistressSelf CareStress, PsychologicalStudentsAdolescentAdultAnxietyCost-Benefit AnalysisDepressionFemaleHumansIndonesiaMalePragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicUniversitiesIndonesiaPsychological distressSelf-help plus (SH+)University students

Identifiers

PMID40629462
PMCPMC12236022

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.