Evidence map›Paper›PMID 40629401›Full record

ArticleCardiovascular ultrasound2025

Validation of noninvasive indices of right ventricular diastolic function. Simultaneous echocardiography and pressure-volume catheterization studies.

Candelas Pérez Del Villar, Raquel Prieto-Arévalo, Jorge García-Carreño, Pablo Martínez-Legazpi, Daniel Rodríguez-Pérez, Yolanda Benito, Antonia Delgado-Montero, J Carlos Antoranz, M Mar Desco, Cristian Herrera Flores and 3 more

Abstract readValidation Study
In one paragraph

Article in Cardiovascular ultrasound, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Candelas Pérez Del Villar *Department of Cardiology, Complejo Asistencial Universitario de Salamanca, Gerencia Regional de Salud de Castilla y León, Universidad de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain. cperezdelvillar@usal.es.ORCID http://orcid.org/0000-0002-2464-4893
Raquel Prieto-Arévalo *Department of Cardiology, Facultad de Medicina, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain. raquel.prieto@salud.madrid.org.
Jorge García-CarreñoDepartment of Cardiology, Facultad de Medicina, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Pablo Martínez-LegazpiDepartment of Cardiology, Facultad de Medicina, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Daniel Rodríguez-PérezDepartment of Mathematical Physics and Fluids, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, Madrid, Spain.
Yolanda BenitoDepartment of Cardiology, Facultad de Medicina, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Antonia Delgado-MonteroDepartment of Cardiology, Facultad de Medicina, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
J Carlos AntoranzDepartment of Mathematical Physics and Fluids, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, Madrid, Spain.
M Mar DescoDepartment of Mathematical Physics and Fluids, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, Madrid, Spain.
Cristian Herrera FloresDepartment of Cardiology, Complejo Asistencial Universitario de Salamanca, Gerencia Regional de Salud de Castilla y León, Universidad de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain.
Rafael Corisco BeltránDepartment of Cardiology, Facultad de Medicina, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Francisco Fernández-AvilésDepartment of Cardiology, Facultad de Medicina, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Javier BermejoDepartment of Cardiology, Facultad de Medicina, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.

Funding

Instituto de Salud Carlos III CM23/00238Instituto de Salud Carlos III JR15/00039Instituto de Salud Carlos III PI12/02885Instituto de Salud Carlos III PI16/01237Instituto de Salud Carlos III,Spain CM12/00273
6 · The paper itself

Abstract

backgroundThe reliability of the recommended echocardiographic methods for assessing RV diastolic function has been questioned. We aimed to validate noninvasive indices of RV diastolic function, derived from tricuspid Doppler and myocardial deformation metrics, against intrinsic diastolic chamber properties and filling pressures.

methodsWe obtained simultaneous high-fidelity pressure-volume loops and echocardiographic data in separate animal and clinical settings: (1) a porcine model of acute hemodynamic interventions (n = 13), and (2) patients with Fallot tetralogy and pulmonary hypertension (n = 9). These designs allow for within- and between-subject validation. From the PV loops data, we obtained the reference values of RV stiffness (S

resultsIn the animal setting, only the tricuspid E/A ratio and e' velocity weakly correlated with S

conclusionsRecommended echocardiographic indices of RV diastolic function do not reflect intrinsic RV diastolic properties. Therefore, the application of these indices for inferring RV diastolic function and filling pressures is limited.

Indexed as

Cardiac CatheterizationEchocardiography, DopplerHeart VentriclesHypertension, PulmonaryStroke VolumeTetralogy of FallotVentricular Dysfunction, RightVentricular Function, RightAdultAnimalsDiastoleDisease Models, AnimalFemaleHumansMaleMiddle AgedDiastolic functionEchocardiographyElastic recoilRelaxationRight ventricleStiffness

Identifiers

PMID40629401
PMCPMC12239245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.