Evidence map›Paper›PMID 40629264›Full record

ArticleBMC genomics2025

Genomic functional annotation and comparative analysis of ABC transporter protein family genes in nine types of Chironomidae insects.

Wenbin Liu, Anmo Zhou, Ziming Shao, Jiaxin Nie, Xinyu Ge, Chuncai Yan, Shaobo Gao, Yiwen Wang

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Wenbin LiuTianjin Key Laboratory of Conservation and Utilization of Animal Diversity, College of Life Sciences, Tianjin Normal University, Tianjin, 300387, China.
Anmo ZhouTianjin Key Laboratory of Conservation and Utilization of Animal Diversity, College of Life Sciences, Tianjin Normal University, Tianjin, 300387, China.
Ziming ShaoTianjin Key Laboratory of Conservation and Utilization of Animal Diversity, College of Life Sciences, Tianjin Normal University, Tianjin, 300387, China.
Jiaxin NieTianjin Key Laboratory of Conservation and Utilization of Animal Diversity, College of Life Sciences, Tianjin Normal University, Tianjin, 300387, China.
Xinyu GeTianjin Key Laboratory of Conservation and Utilization of Animal Diversity, College of Life Sciences, Tianjin Normal University, Tianjin, 300387, China.
Chuncai YanTianjin Key Laboratory of Conservation and Utilization of Animal Diversity, College of Life Sciences, Tianjin Normal University, Tianjin, 300387, China. skyycc@tjnu.edu.cn.
Shaobo GaoGrassland Research Institute of Chinese Academy of Agricultural Sciences, Hohhot, China. gaoshaobo@caas.Cn.
Yiwen WangSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin, 300072, China. yiwen.wang@tju.edu.cn.

Funding

National Natural Science Foundation of China 32370489, 32170473, 32400357Scientific Research Program of the Tianjin Municipal Education Commission 2021KJ151
6 · The paper itself

Abstract

backgroundThe ABC (ATP-binding cassette) transporter family constitutes one of the most extensive transmembrane transporter gene families found across all realms of life. In insects, ABC transporters are crucial for processes such as nutrient metabolism, regulating metamorphosis, and detoxifying xenobiotics. Chironomidae, a diverse aquatic insect group of significant ecological importance that does not bite, has lacked comprehensive annotation of ABC transporters, with the exception of our recent work on Propsilocerus akamusi. In this study, we broaden the annotation by detecting ABC transporter genes across eight additional Chironomidae species, which include all accessible genomes.

resultsA total of 454 ABC transporter genes were annotated across the eight species, categorized into eight distinct subfamilies: 67 belonging to the ABCA subfamily, 45 to ABCB, 105 to ABCC, 13 to ABCD, eight to ABCE, 23 to ABCF, 114 to ABCG, and 78 to ABCH. Phylogenetic analysis using Drosophila melanogaster as an external reference revealed clear orthologous relationships for most Chironomidae ABC transporters, except for a notable expansion of the ABCH subfamily.

conclusionsThis research offers crucial understanding of the evolutionary processes and physiological roles played by ABC transporters within the Chironomidae species, offering a foundation for understanding their role in the environmental adaptability of these species.

Indexed as

ATP-Binding Cassette TransportersChironomidaeGenomicsInsect ProteinsMolecular Sequence AnnotationMultigene FamilyAnimalsEvolution, MolecularGenome, InsectPhylogenyATP-Binding Cassette TransportersInsect ProteinsATP-binding cassette transporterEnvironmental adaptabilityGene annotationNo biting midges

Identifiers

PMID40629264
PMCPMC12236025

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