Evidence map›Paper›PMID 40629187›Full record

ArticleAnnals of intensive care2025

Intra-hospital transport of adult critically ill patients treated with high flow nasal cannula oxygen: a prospective observational multicenter study.

Mai-Anh Nay, Alice Bisson, Adrien Auvet, Agathe Delbove, Aziz Berrouba, Toufik Kamel, Maxime Desgrouas, Thierry Boulain

Registry-linked trialAbstract read
In one paragraph

Article in Annals of intensive care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05311007 (Intrahospital Transport in Patients With High-flow Nasal Oxygenation), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05311007 completednot on this map

Intrahospital Transport in Patients With High-flow Nasal Oxygenation: Prospective Observational Study.

TypeobservationalSponsorCentre Hospitalier Régional d'OrléansRan2022 to 2024Enrolled175ConditionsCritical IllnessArmsEvaluation of the incidence and nature of adverse events
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mai-Anh NayMédecine Intensive Réanimation, Centre Hospitalier Universitaire d'Orléans, Orléans, France. mai-anh.nay@chu-orleans.fr.ORCID http://orcid.org/0000-0002-6116-4987
Alice BissonDépartement d'anesthésie-réanimation, Centre Hospitalier Régional Universitaire de Tours, Tours, France.
Adrien AuvetRéanimation Médico-Chirurgicale, Centre Hospitalier de Dax, Dax, France.
Agathe DelboveService de réanimation polyvalente, Centre Hospitalier Bretagne Atlantique, Vannes, France.
Aziz BerroubaRéanimation polyvalente, Centre Hospitalier de Martigues, Martigues, France.
Toufik KamelMédecine Intensive Réanimation, Centre Hospitalier Universitaire d'Orléans, Orléans, France.
Maxime DesgrouasMédecine Intensive Réanimation, Centre Hospitalier Universitaire d'Orléans, Orléans, France.
Thierry BoulainMédecine Intensive Réanimation, Centre Hospitalier Universitaire d'Orléans, Orléans, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute respiratory failure is a common reason for admission to the intensive care unit, and patients are frequently treated with high-flow nasal cannula oxygen therapy (HFNC). Intra-hospital transport of critically ill patients, such as between hospital wards and the intensive care unit or for diagnostic exams, is common. Transportable HFNC can be used during these intra-hospital transports. We aimed to evaluate the complications associated with intra-hospital transport of patients treated with HFNC.

methodsWe conducted a prospective, descriptive multicenter study between May 2022 and May 2024, involving critically ill adult patients who were treated with HFNC prior to transport and required intra-hospital transport for any reason, accompanied by an intensive care unit team. The primary objective was to evaluate the incidence of severe adverse events including severe hypoxemia (with pulse oxygen saturation of less than 80%), need for intubation, need for non-invasive ventilation or cardiorespiratory arrest during transport. Secondary objectives were to assess the incidence of non-severe adverse events, defined as the need for increased inspired oxygen fraction, switching HFNC for standard oxygen therapy, nasal cannula removal or dysfunction of the HFNC device.

resultsWe included 165 patients and analyzed 187 transports. Eight (4.3%) severe adverse events occurred in 7 patients including 6 cases of severe transient hypoxemia and 2 cases of non-invasive ventilation. All of them were transient severe hypoxemia that occurred during the first transport. Forty-three (23%) non-severe adverse events occurred, including 29(15.6%) cases of increased inspired oxygen fraction requirement, 7/187 (3.74%) cases of nasal cannula removal, 6/187 (3.2%) cases of HFNC device dysfunction, and 1 (0.5%) case involved replacing HFNC with standard oxygen therapy.

conclusionHFNC during intra-hospital transport of critically ill patients had a low incidence of severe adverse events. Non-severe adverse events were more frequent, but their potential impact could not be assessed in this study and warrants further investigation.

trial registrationClinicalstrials.gov, NCT05311007, registered 23 March 2022, https://clinicaltrials.gov/study/NCT05311007?term=hospiflow&rank=1 .

Indexed as

Critical ill patientHigh flow nasal cannulaIntensive care unitIntra-hospital transportOxygenation

Identifiers

PMID40629187
PMCPMC12238688

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.