Evidence map›Paper›PMID 40629137›Full record

ArticleJournal of general internal medicine2026

A Health Literacy Intervention Targeting Chronic Kidney Disease Patients and Healthcare Professionals is Cost-saving: Findings from the Netherlands.

Matheus S Gurgel do Amaral, Marco D Boonstra, Simon van der Pol, Ofer Engel, Gerjan J Navis, Sijmen A Reijneveld, Andrea F de Winter

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matheus S Gurgel do AmaralUniversity of Groningen, University Medical Center Groningen, Department of Health Sciences, Community and Occupational Medicine, Groningen, Groningen, The Netherlands. m.silva.gurgel.do.amaral@umcg.nl.ORCID 0000-0002-8830-4687
Marco D BoonstraUniversity of Groningen, University Medical Center Groningen, Department of Health Sciences, Community and Occupational Medicine, Groningen, Groningen, The Netherlands.ORCID 0000-0001-8807-3068
Simon van der PolUniversity of Groningen, University Medical Center Groningen, Department of Health Sciences, Community and Occupational Medicine, Groningen, Groningen, The Netherlands.ORCID 0000-0003-1784-1001
Ofer EngelUniversity of Groningen, University Medical Center Groningen, Department of Health Sciences, Community and Occupational Medicine, Groningen, Groningen, The Netherlands.ORCID 0000-0002-9675-0599
Gerjan J NavisUniversity of Groningen, University Medical Center Groningen, Department of Nephrology, Groningen, Groningen, The Netherlands.
Sijmen A ReijneveldUniversity of Groningen, University Medical Center Groningen, Department of Health Sciences, Community and Occupational Medicine, Groningen, Groningen, The Netherlands.ORCID 0000-0002-1206-7523
Andrea F de WinterUniversity of Groningen, University Medical Center Groningen, Department of Health Sciences, Community and Occupational Medicine, Groningen, Groningen, The Netherlands.ORCID 0000-0002-9380-4889

Funding

Nierstichting 17SWO06
6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is a progressive disease with high societal costs. CKD progression is influenced by patients' health literacy, i.e., the patients' ability to deal with information related to their own health.

objectiveTo assess the cost-effectiveness of Grip on Your Kidneys (GoYK), a multi-component health literacy intervention for CKD patients and their healthcare professionals. DESIGN AND MAIN MEASURES: We performed a cost-utility analysis of the GoYK intervention, measuring health outcomes in terms of quality-adjusted life years (QALYs) and costs in euros, and extrapolated the results to a lifetime horizon using a Markov model. SUBJECTS: The GoYK study was a quasi-experimental study involving 147 patients with CKD and 48 healthcare professionals from Dutch general practices and nephrology clinics, followed over nine months. KEY

resultsWe found that the GoYK intervention would yield a cost-saving of €28,616 and a gain of 0.37 QALYs per CKD patient across the life course. Moreover, GoYK would avert 31 deaths and 113 new dialyses per 1,000 patients in the first 10 years. These results mainly stemmed from the intervention effect on the transition to end-stage renal disease, where reductions of as little as 1% would already mean GoYK is cost-saving. The intervention remained cost-effective in multiple sensitivity and scenario analyses.

conclusionsGoYK might be a solution to slow CKD progression and, thereby, reduce CKD costs. Given these promising findings and the novelty of our study, further research should confirm our findings before broad implementation.

Indexed as

Cost SavingsHealth LiteracyHealth PersonnelPatient Education as TopicRenal Insufficiency, ChronicAdultAgedCost-Benefit AnalysisFemaleHumansMaleMiddle AgedNetherlandsQuality-Adjusted Life Yearschronic kidney diseasecost-effectivenesshealth literacyhypertensionintervention

Identifiers

PMID40629137
PMCPMC13009444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.