Evidence map›Paper›PMID 40629074›Full record

ArticleInternational journal of impotence research2026

The impact of solid organ transplantation on sexual dysfunction and infertility in older men and women: A Claims Based Study.

Obinna Obuekwe, Haley Clark, Gal Saffati, Tatyana Yatsenko, Laura Oscar-Thompson, Carlos Riveros, Akhil Muthigi

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Article in International journal of impotence research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Obinna ObuekweDepartment of Urology, Houston Methodist Hospital, Houston, TX, USA.ORCID http://orcid.org/0009-0000-7202-0076
Haley ClarkSchool of Engineering Medicine, Texas A&M University, Houston, TX, USA.ORCID http://orcid.org/0009-0004-7804-6778
Gal SaffatiScott Department of Urology, Baylor College of Medicine, Houston, TX, USA.ORCID http://orcid.org/0009-0005-3053-5828
Tatyana YatsenkoDepartment of Urology, Houston Methodist Hospital, Houston, TX, USA.
Laura Oscar-ThompsonDepartment of Urology, Houston Methodist Hospital, Houston, TX, USA.
Carlos RiverosDepartment of Urology, Houston Methodist Hospital, Houston, TX, USA.
Akhil MuthigiDepartment of Urology, Houston Methodist Hospital, Houston, TX, USA. akhilmuth@gmail.com.ORCID http://orcid.org/0000-0001-5885-3653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Solid organ transplantation (SOT) restores organ function and prolongs survival, but its impact on sexual dysfunction and infertility is underexplored. This study evaluated changes in their prevalence before and after transplantation across organ types. We conducted a retrospective cohort study using TriNetX, including 64 932 U.S. adults (≥18 years) who underwent heart, kidney, liver, lung, or pancreas transplants within the past 20 years. Sexual dysfunction (e.g., erectile dysfunction, dyspareunia) and infertility were identified using ICD-10 codes. Pre-post analysis assessed relative and absolute risk reduction (ARR). Analyses were stratified by sex and organ type. SOT was associated with reduced sexual dysfunction (ARR 1.40%, p < 0.001) and infertility (ARR 0.10%, p = 0.013). Males experienced a greater reduction in sexual dysfunction (ARR 2.11%, p < 0.001) than females (ARR 0.20%, p = 0.035). Sexual dysfunction declined following heart (ARR 2.21%, p = 0.001), kidney (ARR 1.42%, p < 0.001), lung (ARR 1.24%, p = 0.042), and liver (ARR 0.74%, p = 0.003) transplants. No difference was seen following pancreas transplantation, and infertility prevalence did not differ across SOT types. These findings suggest SOT may improve sexual health, particularly in men, though effects on infertility remain limited.

Indexed as

InfertilityOrgan TransplantationSexual Dysfunction, PhysiologicalAdultAgedFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesUnited States

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.