Evidence map›Paper›PMID 40629062›Full record

ArticleScientific reports2025

Explainable deep learning approaches for high precision early melanoma detection using dermoscopic images.

Md Abdullah All Mahmud, Sadia Afrin, M F Mridha, Sultan Alfarhood, Dunren Che, Mejdl Safran

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Cross-Disciplinary Mechanistic Insights in Molecular Medicine.Current issues in molecular biology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Md Abdullah All MahmudDepartment of Computer Science, American International University-Bangladesh, Dhaka, Bangladesh.ORCID https://orcid.org/0009-0008-2568-9066
Sadia AfrinDepartment of Computer Science and Engineering, World University of Bangladesh, Dhaka , Bangladesh.ORCID https://orcid.org/0009-0009-9444-4254
M F MridhaDepartment of Computer Science, American International University-Bangladesh, Dhaka, Bangladesh. firoz.mridha@aiub.edu.ORCID https://orcid.org/0000-0001-5738-1631
Sultan AlfarhoodDepartment of Computer Science, College of Computer and Information Sciences, King Saud University, P.O. Box 51178, Riyadh, Saudi Arabia.ORCID https://orcid.org/0009-0001-1268-9613
Dunren CheDepartment of Electrical Engineering and Computer Science, Texas A&M University-Kingsville, Kingsville, 78363, Texas, USA.ORCID https://orcid.org/0000-0002-9906-4295
Mejdl SafranDepartment of Computer Science, College of Computer and Information Sciences, King Saud University, P.O. Box 51178, Riyadh, Saudi Arabia. mejdl@ksu.edu.sa.ORCID https://orcid.org/0000-0002-7445-7121

Funding

King Saud University ORF-2025-1027
6 · The paper itself

Abstract

Detecting skin melanoma in the early stage using dermoscopic images presents a complex challenge due to the inherent variability in images. Utilizing dermatology datasets, the study aimed to develop Automated Diagnostic Systems for early skin cancer detection. Existing methods often struggle with diverse skin types, cancer stages, and imaging conditions, highlighting a critical gap in reliability and explainability. The novel approach proposed through this research addresses this gap by utilizing a proposed model with advanced layers, including Global Average Pooling, Batch Normalization, Dropout, and dense layers with ReLU and Swish activations to improve model performance. The proposed model achieved accuracies of 95.23% and 96.48% for the two different datasets, demonstrating its robustness, reliability, and strong performance across other performance metrics. Explainable AI techniques such as Gradient-weighted Class Activation Mapping and Saliency Maps offered insights into the model's decision- making process. These advancements enhance skin cancer diagnostics, provide medical experts with resources for early detection, improve clinical outcomes, and increase acceptance of Deep Learning-based diagnostics in healthcare.

Indexed as

Deep LearningDermoscopyEarly Detection of CancerMelanomaSkin NeoplasmsHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedReproducibility of ResultsDeep learningDermoscopic imagesEarly-stage melanoma detectionExplainable AISwish activation

Identifiers

PMID40629062
PMCPMC12238264

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.