ArticleScientific reports2025
Evaluating bioassay efficacy of extremophile bacillus species for environmentally safe control of Aedes aegypti larvae.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Exploitation of Endemic Extremophilic Microbial Strains Isolated from Date Palm Fibrillium in the Saoura Region (Southwest Algeria) as Potential Biocontrol Agents Against Mosquitoes.Journal of arthropod-borne diseases · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
Mosquito-borne diseases pose significant public health challenges, necessitating innovative and sustainable control measures. This study evaluates the larvicidal potential of six extremophile Bacillus species against Aedes aegypti larvae, focusing on dose-response relationships, resistance trends, and genetic diversity. Regression analysis revealed a significant positive correlation between concentration and larval mortality across species, with B. sonorensis and B. paramycoides demonstrating superior potency at lower concentrations (LC₅₀: 19.72 ppm and 23.41 ppm, respectively). Probit analysis confirmed that B. sonorensis is the most effective larvicide, achieving high mortality rates with minimal concentrations. In contrast, B. licheniformis and B. stercoris exhibited limited efficacy, requiring significantly higher doses to achieve comparable results. Resistance analysis highlighted an inverse relationship between toxicity index and resistance ratio, with B. sonorensis maintaining high efficacy even in resistant mosquito populations (Resistance Ratio: 1). Furthermore, phylogenetic analysis based on 16S rRNA gene sequences revealed distinct evolutionary relationships among species, with B. rugosus and B. tequilensis clustering closely, suggesting functional similarities. The genetic divergence of B. licheniformis aligns with its lower larvicidal performance. Overall, this study underscores the potential of B. sonorensis and B. paramycoides as robust candidates for mosquito control programs, particularly in resistance-prone environments. The findings provide valuable insights into optimizing microbial larvicides by tailoring species-specific application strategies and leveraging genetic diversity within the Bacillus genus.
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