Evidence map›Paper›PMID 40629033›Full record

ArticleScientific reports2025

Competitive exclusion approach using an E. coli live vaccine to protect broilers from colonization with ESBL-/ pAmpC- E. coli.

Diana Vargas, Roswitha Merle, Anika Friese, Uwe Roesler, Caroline Robé

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diana VargasVeterinary Centre for Resistance Research, Institute of Animal Hygiene and Environmental Health, Freie Universität Berlin, Berlin, Germany. diana.vargas.gallo@fu-berlin.de.
Roswitha MerleVeterinary Centre for Resistance Research, Institute of Veterinary Epidemiology and Biostatistics, Freie Universität Berlin, Berlin, Germany.
Anika FrieseVeterinary Centre for Resistance Research, Institute of Animal Hygiene and Environmental Health, Freie Universität Berlin, Berlin, Germany.
Uwe RoeslerVeterinary Centre for Resistance Research, Institute of Animal Hygiene and Environmental Health, Freie Universität Berlin, Berlin, Germany.
Caroline RobéVeterinary Centre for Resistance Research, Institute of Animal Hygiene and Environmental Health, Freie Universität Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial-resistant bacteria originating from broilers pose an ongoing challenge as they can spread in the environment and food chain. One approach to lower colonization is to administer live bacteria to broilers. A live Escherichia coli (E. coli) vaccine, consisting of a single E. coli strain used as a competitive exclusion (CE) approach, was evaluated to decrease the colonization with ESBL-/pAmpC- producing E. coli. 168 ESBL-/pAmpC- negative Ranger Gold broilers were divided into six groups (3 x n = 46 experimental groups; 3 x n = 10 control groups for quality assurance). The E. coli vaccine was administered on day one through coarse spray or by drinking water on day five. Experimental groups were orally co-colonized with 10

Indexed as

ChickensEscherichia coliEscherichia coli InfectionsEscherichia coli VaccinesPoultry DiseasesAnimalsbeta-LactamasesVaccines, Attenuatedbeta-LactamasesEscherichia coli VaccinesVaccines, AttenuatedAntimicrobial resistanceBroiler chickenCompetitive exclusionESBLEscherichia colipAmpC

Identifiers

PMID40629033
PMCPMC12238256

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.