Evidence map›Paper›PMID 40628532›Full record

ReviewJournal of experimental botany2025

Not to be overlooked: dipeptides and their role in plant stress resilience.

Pallavi Agarwal, Hillary D Fischer, Maria D Camalle, Aleksandra Skirycz

Abstract readReview
In one paragraph

Review in Journal of experimental botany, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Integrative physiological and metabolomic study of Hirschfeldia incana under short- and medium-term lead (Pb) stress.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Article
  3. Article
  4. Discovery of Tyrosinase Inhibitors fromCurrent issues in molecular biology · 2026
    Article
  5. AFrontiers in plant science · 2026
    Article
  6. Differential modulation of tomato root exudates byFrontiers in plant science · 2026
    Article
  7. Peptides: powerful, pervasive, and full of potential.Journal of experimental botany · 2025
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pallavi AgarwalMichigan State University, East Lansing, MI 48823, USA.
Hillary D FischerMichigan State University, East Lansing, MI 48823, USA.
Maria D CamalleMichigan State University, East Lansing, MI 48823, USA.ORCID 0000-0002-6299-1124
Aleksandra SkiryczMichigan State University, East Lansing, MI 48823, USA.ORCID 0000-0002-7627-7925

Funding

Protein-metabolite interaction networks for functional characterization of metabolites.R35GM153298 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Aleksandra Skirycz · 2024 to 2026
$1.2M
NIGMS NIH HHS R35 GM153298NIH HHS R35GM153298
6 · The paper itself

Abstract

Dipeptides are structurally diverse small molecules with varying modes of biogenesis and function. In plants, dipeptides were historically associated with nitrogen storage and mobilization; however, they are also reported to act as antioxidants, signaling molecules, protein regulators, and modulators of microbial communities. In this review, we discuss the structural diversity and biogenesis of dipeptides, with respect to (i) proteinogenic dipeptides that are products of protein degradation, (ii) non-proteinogenic amino acid dipeptides, such as those containing a γ-glutamyl group, and (iii) cyclic dipeptides, largely derived from microorganisms. Highlighted are recent examples of dipeptides that were shown to display plant health-promoting activities, including boosting growth and improving stress resilience against pathogens, salinity, chilling, and heat, making the case that these overlooked compounds are more than what meets the eye.

Indexed as

DipeptidesPlant Physiological PhenomenaPlantsStress, PhysiologicalDipeptidesCyclic dipeptidesdipeptidesplant growthstress resilienceγ-glutamyl dipeptides

Identifiers

PMID40628532
PMCPMC12516527

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.