Evidence map›Paper›PMID 40628003›Full record

ArticlePsychiatry research2025

Prenatal obsessive beliefs predict postpartum obsessive-compulsive symptoms: a prospective study.

Jonathan S Abramowitz, Samantha N Hellberg, Janice Krasnow, Joseph B Friedman, Nicholas S Myers, Paul S Nestadt, Heidi J Ojalehto, Emily K Juel, Jack Samuels, Mary E Kimmel and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatry research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jonathan S AbramowitzDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: jabramowitz@unc.edu.
Samantha N HellbergDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Janice KrasnowDepartment of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Joseph B FriedmanDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Nicholas S MyersDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Paul S NestadtDepartment of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Heidi J OjalehtoDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Emily K JuelDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jack SamuelsDepartment of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mary E KimmelDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Lauren M OsborneDepartment of Obstetrics and Gynecology and Department of Psychiatry, Weil Cornell Medical College, NY, NY, USA.
Eric A StorchDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Gerald NestadtDepartment of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Rashelle J MusciBloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Funding

2/2 Predictors and Course of Postpartum Obsessions and CompulsionsR01MH118261 · NIMH · JOHNS HOPKINS UNIVERSITY · PI NESTADT, GERALD · 2019 to 2023
$2.1M
1/2 Predictors and Course of Postpartum Obsessions and CompulsionsR01MH118249 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ABRAMOWITZ, JONATHAN S. · 2019 to 2023
$1.5M
NIMH NIH HHS R01 MH118249NIMH NIH HHS R01 MH118261
6 · The paper itself

Abstract

This longitudinal study examined whether specific cognitive patterns during pregnancy predict postpartum obsessive-compulsive (OC) symptoms. A diverse sample of 256 women was assessed at 20 weeks of pregnancy (Time 1), 6 weeks postpartum (Time 2; n = 233), and 6 months postpartum (Time 3; n = 231). At each point, participants completed interview and/or self-report measures of OC symptoms, psychological distress, and obsessive beliefs (i.e., cognitive patterns related to OC symptoms). Postpartum OC symptoms were common, reported by 87.1 % at Time 2 and 74.5 % at Time 3. Stronger prenatal obsessive beliefs during pregnancy predicted greater postpartum OC symptom severity and higher likelihood of an OCD diagnosis at Time 3, even after controlling for baseline OC symptoms and distress. Findings highlight the clinical importance of prenatal cognitive risk factors and support cognitive-behavioral models of postpartum OCD.

Indexed as

Obsessive-Compulsive DisorderPostpartum PeriodPregnancy ComplicationsAdultFemaleHumansLongitudinal StudiesPregnancyProspective StudiesYoung AdultCognitive-behavioral modelIntrusive thoughtsLongitudinal studyObsessive beliefsPostpartum OCD

Identifiers

PMID40628003
PMCPMC12321878

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.