Observational studyJMIR cardio2025
Improving the Readability of Institutional Heart Failure-Related Patient Education Materials Using GPT-4: Observational Study.
Observational study in JMIR cardio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The trial behind it
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Who cites it
7 citing papers in PubMed.
- Artificial intelligence to support clinical practice across the inpatient heart failure care pathway: a systematic review.European heart journal. Digital health · 2026Review
- Assessment of AI-Generated Patient Education Materials for Bladder Training and Pelvic Floor Muscle Therapy: Comparison with an International Society Leaflet.International urogynecology journal · 2026Article
- ChatGPT and Gemini in warfarin counseling.Croatian medical journal · 2026Article
- Challenges of using generative AI for patient education in chronic heart failure: an evaluation of content quality, readability, and actionability in cross-platform LLM-generated texts.Frontiers in public health · 2026Article
- Benchmarking the readability, quality, and educational suitability of large language models in communicating pertussis.Frontiers in public health · 2026Article
- ChatGPT Applications in Heart Failure: Patient Education, Readability Enhancement, and Clinical Utility.Journal of cardiovascular development and disease · 2025Review
- Readability of Chatbot Responses in Prostate Cancer and Urological Care: Objective Metrics Versus Patient Perceptions.Current oncology (Toronto, Ont.) · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Heart failure management involves comprehensive lifestyle modifications such as daily weights, fluid and sodium restriction, and blood pressure monitoring, placing additional responsibility on patients and caregivers, with successful adherence often requiring extensive counseling and understandable patient education materials (PEMs). Prior research has shown PEMs related to cardiovascular disease often exceed the American Medical Association's fifth- to sixth-grade recommended reading level. The large language model (LLM) ChatGPT may be a useful tool for improving PEM readability. Objective: We aim to assess the readability of heart failure-related PEMs from prominent cardiology institutions and evaluate GPT-4's ability to improve these metrics while maintaining accuracy and comprehensiveness. Methods: A total of 143 heart failure-related PEMs were collected from the websites of the top 10 institutions listed on the 2022-2023 US News & World Report for "Best Hospitals for Cardiology, Heart & Vascular Surgery." PEMs were individually entered into GPT-4 (version updated July 20, 2023), preceded by the prompt, "Please explain the following in simpler terms." Readability was assessed using the Flesch Reading Ease score, Flesch-Kincaid Grade Level (FKGL), Gunning Fog Index, Coleman-Liau Index, Simple Measure of Gobbledygook Index, and Automated Readability Index. The accuracy and comprehensiveness of revised GPT-4 PEMs were assessed by a board-certified cardiologist. Results: For 143 institutional heart failure-related PEMs analyzed, the median FKGL was 10.3 (IQR 7.9-13.1; high school sophomore) compared to 7.3 (IQR 6.1-8.5; seventh grade) for GPT-4's revised PEMs (P<.001). Of the 143 institutional PEMs, there were 13 (9.1%) below the sixth-grade reading level, which improved to 33 (23.1%) after revision by GPT-4 (P<.001). No revised GPT-4 PEMs were graded as less accurate or less comprehensive compared to institutional PEMs. A total of 33 (23.1%) GPT-4 PEMs were graded as more comprehensive. Conclusions: GPT-4 significantly improved the readability of institutional heart failure-related PEMs. The model may be a promising adjunct resource in addition to care provided by a licensed health care professional for patients living with heart failure. Further rigorous testing and validation is needed to investigate its safety, efficacy, and impact on patient health literacy.
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