Evidence map›Paper›PMID 40627823›Full record

ArticleJCO clinical cancer informatics2025

Assessing the Data Quality Dimensions of Surgical Oncology Cohorts in the

Matthew Spotnitz, John Giannini, Emily Clark, Yechiam Ostchega, Tamara R Litwin, Stephanie L Goff, Lew Berman

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matthew SpotnitzAll of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD.ORCID 0000-0003-2869-0237
John GianniniAll of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD.ORCID 0000-0001-7626-6540
Emily ClarkGAP Solutions, Inc, Herndon, VA.ORCID 0000-0002-0039-0470
Yechiam OstchegaAll of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD.ORCID 0009-0001-8054-9727
Tamara R LitwinAll of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD.
Stephanie L GoffSurgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.ORCID 0000-0003-3317-9804
Lew BermanAll of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD.

Funding

Intramural NIH HHS Z99 OD999999
6 · The paper itself

Abstract

purposeCancer is a leading cause of morbidity and mortality in the United States. Mapping electronic health record (EHR) data to the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM) may standardize data structure and allow for multiple database oncology studies. However, the number of oncology studies produced with the OMOP CDM has been low. To investigate the discrepancy between the public health impact of cancer and the output of OMOP CDM clinical cancer studies, we evaluated (EHR) data quality of five surgical oncology cohorts in the

methodsWe selected procedure codes that were the basis of each phenotype. We used a data quality checklist to evaluate five domains systematically: conformance, completeness, concordance, plausibility, and temporality.

resultsMost phenotype-defining source codes were mapped to Current Procedural Terminology 4, which is an EHR standard. All cohorts had low concept prevalence. Most bivariate correlations between concepts were weak (⍴ ≤ 0.5). The small number of biomarkers available for use limited our plausibility analysis. The median time between biopsy and surgery varied across cohorts.

conclusionWe identified multiple data completeness issues, which limited the fitness for use evaluation. Also, using the OMOP CDM procedure concepts and mappings presented challenges for our study. Variable amounts of missingness in OMOP CDM surgical oncology data may affect the fitness for use of cancer data. Further research is warranted to improve the quality of that data.

Indexed as

Data AccuracyElectronic Health RecordsNeoplasmsSurgical OncologyCohort StudiesHumansMedical OncologyUnited States

Identifiers

PMID40627823
PMCPMC12240465

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